Endocrine Abstracts (2019) 65 P421 | DOI: 10.1530/endoabs.65.P421

Analysis of the outcome of repeat Fine Needle Aspiration Cytology for Thy3a thyroid nodules - a retrospective study of 4 year data in a district general hospital

Dilip Nair


Royal Berkshire NHS Foundation Trust, Reading, UK


Introduction: Thy3 classification was subdivided into Thy3a and Thy3f to reduce the dilemma and confusion surrounding the management of patients with indeterminate thyroid nodules. Thy3a lesions are often downgraded or upgraded on repeat sampling and in thyroid MDT.

Patients and method: A retrospective analysis of the patients who had thy3a diagnosis from January 2015 until December 2018 was recorded. All patients who underwent a second sampling were included whereas patients who did not have complete data and private patients were excluded.

Results: Of 54 patients with Thy3a results, 43 were included in the study (6 males, 37 females). Of these, 17 patients underwent a second FNA (39.5%). Eight of these seventeen patients (47%) were downgraded to thy2 on repeat FNA. Of these 4 (50%) did not proceed to surgery and were discharged whereas 4 (50%) who proceeded with surgery had a benign final histology.

Conclusion: Thy3a results do have a moderate risk of malignancy but repeat sampling as shown in our analysis does show evidence of the need to carefully interpret the first sampling outcome and need to consider repeat FNA or MDT discussion to avoid unnecessary surgery for a benign lesion.

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