Endocrine Abstracts

Objective: To identify the radiological characteristics of adrenal abnormalities as reported on CT abdomen;To identify functional characteristics of adrenal incidentalomas; To identify 12 month outcomes of adrenal incidentalomas

1500 consecutive unselected computerised Tomograms(CT abdomen) done for non-adrenal indication, reviewed for adrenal abnormalities to identify, the incidence size, radiological density, those with abnormalities underwent endocrine work-up and re-imaging as advised in the European endocrine society guidelines.1500 scan were reviewed, Total abnormalities identified in the adrenal in 60 scans. Adrenal Adenomas wereidentified in 55, of which 1 was >4 cm, 1 were 3-4 cms in size, 5 in the 2-3 cm range, 18 in the 1-2 cm range and 30 in the sub centimetre range. 5 non-specific abnormalities were also identified.75% of all lesions were non-functioning adenomas. 12% had non-suppressed cortisol on overnight 1 mg Dexamethasone suppression. 2% patients had features of aldosterone over secretion, and 1 percent had phaeochrochromocytoma. Repeat scanning at 12 months was done on 25 of these adenomas that were ≥ 1 cm and no significant interval change in their size or appearance was identified in any of the adrenal incidentalomas on re-imaging. Our study is the first study of adrenal incidentalomas in the Irish midlands and broadly confirms the accepted European prevalence of adrenal incidentalomas of 0.04% for CT abdomen. Furthermore, it demonstrates that functionally 1 out of every 5 of the adrenal incidentaloma may have features of adrenal autonomous secretion. And cortisol oversecretion was the commonest endocrine abnormality detected in this cohort.