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Endocrine Abstracts (2020) 70 EP399 | DOI: 10.1530/endoabs.70.EP399

ECE2020 ePoster Presentations Reproductive and Developmental Endocrinology (37 abstracts)

The role of E2/P ratio in the etiology benign breast disease and mastopathy

Milena Brkic 1 & Svetlana Vujovic 2

1Faculty of medicine University of Banja Luka, Banja Luka, Bosnia and Herzegovina, BanjaLuka, Bosnia and Herzegovina; 2School of Medicine, University of Belgrade, Belgrade, Serbia, Department of Endocrinology, Clinical Center of Serbia, Beograd, Serbia

The aim of the study was to assess the role of the estradiol and progesterone relationship during the late luteal phase and the occurrence of fibrocystic breast disease (FBD). The concentration of E2/P was measured in the group of women with FBD as study group and healty control group. All women had regular ovulation cycles. Blood samples for E2, P and prolactin determination were obtained in the morning at 8 am on days 21 and 24 of menstrual cycle. Significant mastalgia and mastodynia history in women with FBD was obtained with yes or no questionnaire. FBD diagnosis was confirmed with ultrasound. In the control group, a reduced E2/P ratio was noticed from day 21 to day 24 of the cycle, which was not recorded in the group of women with FBD (study group). Even the slightest disturbance of the E2/P ratio may contribute to the occurrence of benign breast disease with clinical manifestations of mastalgia and mastodynia.

Volume 70

22nd European Congress of Endocrinology

05 Sep 2020 - 09 Sep 2020

European Society of Endocrinology 

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