Endocrine Abstracts

The aim of investigation to study the prevalence rate of precocious puberty (PP) in children by region of the Republic of Uzbekistan (as of December 31, 2018). The prevalence rate of premature sexual development in children by region of the Republic of Uzbekistan (as of December 1, 2018).

Material and Methods: We observed 173 children with true precocious puberty (including boy – 51, girls – 122), which had treatment in regional endocrinology clinics in the period from January 1, 2018 to December, 31, 2018 year. Patients were measured height, weight, considered a lack of growth, weight, performed a palpation of the thyroid gland and an objective examination of sexual development’ stages by Tanner. All patients underwent a set of studies, including the clinical (General blood and urine analysis), biochemical, hormonal (LH, FSH, prolactin, estradiol, progesterone, free testosterone). Besides that, we performed pituitary MRI and ultrasound investigation of endocrine organs.

Results: It was established that as of December 31, 2018 in Andijan region was registered 8 children with PP, in Bukhara region – 32, Djizakh region – 5, Kashkadarya region –2, Navoi region–2, Namangan region-2, Samarkand region –11, Surkhandarya region –42, Tashkent region –9, Fergana region –11, Khorezm region –39, Tashkent city – 5 patients.

Conclusions: The largest number of patients was registered in Surkhandarya region.