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Endocrine Abstracts (2021) 73 AEP117 | DOI: 10.1530/endoabs.73.AEP117

Mohamed VI University Hospital Center, Oujda, Department of Endocrinology-Diabetology and Nutrition, Oujda, Morocco


Turner syndrome is one of the most common chromosomal disorders, with a reported prevalence of 1/2500 live females. It is characterized by short stature, ovarian failure, malformative, autoimmune, skeletal and bone abnormalities. The objective of our work is to study the prevalence of skeletal and bone malformations in our Turnerian patients.

Material and method

This is a retrospective descriptive study realized in 17 patients followed for a Turner syndrome at the Endocrinology-Diabetology and Nutrition Department of the Mohammed VI University Hospital Center of Oujda. The data collected were analyzed using SPSS 25 software.


The mean age of diagnosis was 16.4 ± 12.4 years. Shorte stature was the most frequent reason for consultation in 47% of cases, followed by amenorrhea in 35.3%. Statural retardation was present in all patients, with short legs in 47.1%. Kyphosis was reported in 5.8% of cases with erosions on the anterior surfaces of the vertebrae and layered cervical vertebral compression on MRI, scoliosis in 11.7% and bradymetacarpia in 5.8% of cases. Vitamin D deficiency was objectively diagnosed in all patients with a mean of 18.9 ± 7.2 ng/ml. Osteoporosis (spine and femurs) was observed in 17.6% of cases in patients diagnosed in adulthood with primary amenorrhea not substituted on the hormonal level.


Skeletal and bone deformities are common during turner syndrome. Osteoporosis is still a real problem with its high fracture risk, hence the importance of early hormonal replacement, adequate intake of calcium products and correction of vitamin D deficiency.

Volume 73

European Congress of Endocrinology 2021

22 May 2021 - 26 May 2021

European Society of Endocrinology 

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