Searchable abstracts of presentations at key conferences in endocrinology
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European Congress of Endocrinology 2021

22 May 2021 - 26 May 2021

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The European Congress of Endocrinology provides a global platform for the international endocrine community to discuss the latest advances in the field.


Symposium 21: Hot topics in neuroendocrine tumours

ea0073s21.1 | Symposium 21: Hot topics in neuroendocrine tumours | ECE2021

Epigenetics in NENs – lessons from MEN1-NENs models

Lines Kate

Epigenetic mechanisms are gaining increasing interest in oncology, both as drivers of tumourigenesis and as potential novel therapeutic targets. This is particularly relevant in neuroendocrine neoplasms (NENs), as a key tumour suppressor gene involved in NEN development, multiple endocrine neoplasia type 1 (MEN1), plays a critical role in epigenetic regulation of gene expression through micro RNA (miRNA) and histone modification pathways. MEN1 mutations can g...