Searchable abstracts of presentations at key conferences in endocrinology
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Society for Endocrinology BES 2021

Edinburgh, United Kingdom
08 Nov 2021 - 10 Nov 2021

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Join us in Edinburgh for the flagship event of the Society for Endocrinology

Oral Poster Presentations

Endocrine Cancer and Late Effects

ea0077op6.1 | Endocrine Cancer and Late Effects | SFEBES2021

Incidental findings are common, but rarely clinically significant, in patients with Neuroendocrine Tumours undergoing Gallium68 Dotatate PET CT; results from a one year retrospective review

Garrahy Aoife , Tadman Mike , Slater Viv , Moore Niall , Coupe Nicholas , Weaver Andrew , Soonawalla Zahir , Patel Neel , May Christine , Jafar Mohammadi Bahram

Gallium68-Dotatate PET-CT is a somatostatin-receptor (SSTR) based imaging modality employed in the diagnosis and follow-up of Neuroendocrine Tumours (NET). We set out to investigate the incidence of incidental findings, some of which are related to SSTR expression, in our NET patient cohort in Oxford University Hospital. Sixty-eight patients underwent Gallium68-Dotatate PET-CT between June 2020 and June 2021. 40 patients (59%) were female, and median age ...

ea0077op6.2 | Endocrine Cancer and Late Effects | SFEBES2021

The evaluation of a musculoskeletal health package intervention to prevent bone toxicity in women with gynaecological malignancies undergoing pelvic radiotherapy. The RadBone randomised controlled feasibility study

Grigoriadou Victoria Chatzimavridou , Barraclough Lisa , Baricevic-Jones Ivona , Bristow Robert , Eden Martin , Haslett Kate , Johnson Karen , Kochhar Rohit , Merchant Zoe , Moore John , O’Connell Sarah , Taylor Sally , Westwood Thomas , Whetton Anthony , Yorke Janelle , Higham Claire E

Background: Bone toxicity and more specifically Radiotherapy Related Insufficiency Fractures (RRIFs) are common late effects of pelvic radiotherapy, associated with increased morbidity and reduced quality of life, while their cost to the health system is currently unknown. The mechanisms underlying RRIFs are not well understood. Effective preventive techniques and management pathways need to be developed and validated with robust clinical and health economic analyses. The RadB...

ea0077op6.3 | Endocrine Cancer and Late Effects | SFEBES2021

An unusual presentation of hypoglycaemia: An investigative challenge

Chia Eng Pei , Avari Parizad , Chen Runzi , Spalding Duncan , Oliver Nick , Wernig Florian

Prohormone convertase 1/3 (PC1/3), encoded by protein convertase subtilisin kexin type 1 (PCSK1), converts inactive prohormones such as pro-opiomelanocortin, proinsulin, proglucagon into biologically active peptides. Inherited genomic mutations of PCSK1 present with malabsorptive diarrhoea, hyperinsulinemic hypoglycaemia, central adrenal and thyroid defects and severe obesity. Somatic mutations of insulinomas are associated with genetic defects interfering with insulin secreti...

ea0077op6.4 | Endocrine Cancer and Late Effects | SFEBES2021

Virtual Blood Pressure Monitoring in the Pre-operative Management of Phaeochromocytoma Patients in a Tertiary Centre during the COVID-19 Pandemic

Mile Rebecca , Bi Yixi , Gulamhusein Aziz , Hoong Ho Jan , Adam Safwaan

The usual management at our centre for patients awaiting phaeochromocytoma surgery involves pre-operative titration of alpha blockade with frequent clinic visits for blood pressure (BP) and heart rate (HR) monitoring. The COVID-19 pandemic restricted our ability to consult with patients frequently. To reduce infection risk, we incorporated virtual BP monitoring using a Microsoft Excel template coupled with regular remote consultations. We present a clinical case highlighting o...