SFEBES2021 Poster Presentations Adrenal and Cardiovascular (45 abstracts)
COVID-19 and Adrenal Insufficiency: A retrospective Study at a District General Hospital
Reena Kumari , Mahwish Abid , Saba Hafeez , Devesh Sennik , Jennifer Wallace , Panteliou Eleftheria & Purnami de Silva
Princess Alexandra Hospital, Harlow, United Kingdom
Introduction: Covid -19 can cause serious or severe illness in anyone but those with chronic health conditions are at greater risk. Adrenal insufficiency (AI) is assumed to be associated with an increased Covid-19 infection risk, which could trigger an adrenal crisis. We conducted a retrospective study at district general hospital to assess the incidence of COVID-19 in Adrenal insufficiency patients.
Method and material: Retrospective review of 43 patients who were under the follow up of our endocrine team with primary and secondary adrenal insufficiency was conducted using standardised questionnaire over the telephone. We collected data on COVID-19 symptoms and complications.
Results: Of 43 patients, Covid-19 PCR was positive in 9(21%) patients and negative in 34 (79%) between 1 March 2020 and 30 April 2021. Among the positive patients, 8/9 (88.8%) were symptomatic, and 1/9 (11.11%) was asymptomatic; P value <0.001. Most of patient were above 60, 4/9 (44.44%); P value <0.001. 4/8(50%) patients required hospital admission for oxygen support, but none of them had an adrenal crises; P value<0.001. 1/9 patients required ITU admission (11%).
Conclusions: We concluded that there was overall low risk of contracting covid-19 infection in our adrenal insufficiency patients (21%) but that it is higher than the baseline rate in the general population (6%). There did not appear to be any increased incidence of adrenal crisis in our small DGH sample.
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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