Endocrine Abstracts

During this session on the controversies in the management of neonatal hypoglycaemia, I will discuss why the real controversy is not the definition of hypoglycaemia but rather what we should do when we find low glucose values. I will discuss my preferred hypoglycemia guideline recommendation. In addition I will discuss the relationship between hypoglycemia and brain damage and demonstrate to the audience that hypoglycemia is not the cause of brain damage but rather energy defi...

The hypothalamus integrates the neuroendocrine control of numerous hormonal systems. Energy balance is regulated by a complex neuroendocrine feedback loop, in which the ventromedial hypothalamus (VMH) responds peripheral neural and hormonal afferent signals of satiety and energy reserve (through insulin and leptin), interprets these as anorexigenic (a-MSH) or orexigenic (NPY, AgRP) signals (through the melanocortin-4 receptor), and then directs efferent autonomic signals (symp...