Endocrine Abstracts

Neonatal Diabetes Mellitus (NDM) occurs in the neonatal period and has a very high burden of morbidity and mortality. The incidence is approximately 1:100,000 but reports range from between 1 in 25,000 to 1:500,000 live births. A genetic cause can be found in over 80% of cases. At present, patients with NDM are unrecognised as being seriously ill until hyperglycaemia is at a life-threatening level. An effective method for measuring blood glucose concentrations from Guthrie car...

2021 is an important year for diabetes. It is 100 years since insulin was discovered and the first child had their life saved by insulin, turning a death sentence into a chronic condition. Since then, insulin has remained the mainstay of treatment for type 1 diabetes. Outcomes have improved with advances in technology, but outcomes remain suboptimal and, in the UK, around 25% children still present late, in a state of life-threatening diabetic ketoacidosis (DKA). DKA rates hav...