Searchable abstracts of presentations at key conferences in endocrinology
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UKI NETS 19th National Conference

ea0080OC1 | Oral Communications | UKINETS2021

Incidence, prevalence of survival of neuroendocrine neoplasia in England 1995–2018

White Benjamin E , Chandrakumaran Kandiah , Wong Kwok , Rous Brian , Bouvier Catherine , Van Hemelrijck Mieke , Srirajaskanthan Rajaventhan , Ramage John K

Introduction: Incidence of neuroendocrine neoplasia (NEN) is rising worldwide. The National Cancer Registry and Analysis Service allows accurate study of NEN in England. Aim: Calculate incidence and prevalence of NEN in England from 1995-2018. Calculate site-specific survival with multivariate analysis. Method: A population-based retrospective cohort study was performed. Data requested from NCRAS were reviewed by a steering group r...

ea0080OC2 | Oral Communications | UKINETS2021

Tracking circulating cell free tumour derived DNA in patients with neuroendocrine neoplasms

Gohil Shailesh , Page Karen , Hastings Rob , Iwuji Chinenye , Richards Cathy , Shaw Jacqui , Levy Miles

Introduction: There is a clinical need to develop novel and better biomarkers to monitor patients with neuroendocrine neoplasms (NENs). Our aim was to identify and track plasma circulating cell free tumour derived DNA (ctDNA) in a cohort of patients using a personalised, patient specific approach.Materials and methods: 35 serial plasma samples were collected from 9 patients with metastatic NENs (6 small intestinal and 1 each of lung, ovarian, and pelvic;...

ea0080OC3 | Oral Communications | UKINETS2021

An update on the effects of debulking surgery and liver directed intra-arterial therapies on quality of life in patients with metastatic neuroendocrine tumours

Woods Eleanor , Sinclair Adam , Jarvis Emma , Ramsey Emma , Tanno Lulu , Naheed Salma , Armstrong Thomas , Takhar Arjun , Knight John , Stedman Brian , Modi Sachin , Bryant Timothy , Breen David , Nolan Luke , Al-Mrayat Ma'en , Pearce Neil , Cave Judith

Background: Neuroendocrine tumours (NETs) arise from neuroendocrine cells, they are commonly found in the pancreas, small bowel and lung. They are a heterogeneous group of tumours capable of secreting a variety of hormones, therefore the spectrum of symptoms is broad. Treatment options for metastatic NETs include cytoreductive surgery, or interventional radiology procedures such as transarterial embolization (TAE). Aims: Previous studies have shown that ...