Endocrine Abstracts

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In vitro diagnostics (IVD) in the European Union is facing a fundamental change with the introduction of a new regulation, the so-called In Vitro Diagnostics Regulation (IVDR). Originally, the IVDR was scheduled to enter into force in May 2022, however, in January 2022, the EU legislator made a differentiated partial postponement of the application of important parts of the IVDR. The major innovation and achievement of the IVDR is that most commercially manufactured IVD produc...

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The Daily Tolerable Intake (DTI) was reduced by BPA (bisphenol A) 100,000 fold. This is an unprecedented action to protect consumers and the environment from the most commonly used plasticizer. However, one problem identified was the fact that regrettable substitutes, such as BPS and BPF, were not included in the recommendation. There will be a fight to ensure that this passes into the European legislation. In the meantime, BP-B (,4’-(1-methylpropylidene) bisphenol (a sub...

Hormones are key regulators of numerous physiological processes. While most hormones are produced in select organs, their effects are felt throughout the body. Hormonal exposure is not only mediated by hormone production, but also by circulating binding proteins, and by local metabolism. Although we still heavily rely on total serum levels for the diagnosis of endocrine disorders and abnormalities, it is increasingly clear that total serum hormone levels do not always accurate...