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Endocrine Abstracts (2022) 81 EP463 | DOI: 10.1530/endoabs.81.EP463

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1Hospital Charles Nicolle, Endocrinology, Tunis, Tunisia; 2Hospital Charles Nicolle, Cardiology, Tunis, Tunisia


Introduction: People with high blood pressure have a greater risk of developing diabetes, and people with diabetes also have an increased risk of high blood pressure. These two associated pathologies can increase cardiovascular risks and cause other repercussion such as arterial stiffness. The aim of this study is to examine the relationship between pulse wave velocity and hypertension in type 2 diabetes.

Methods: We conducted a prospective study including 249 diabetic patients without macroangipathic complications, between July 2020 and May 2021. Using a SphygmoCor®XCEL device, we measured arterial stiffness directly by the carotid to femoral pulse wave velocity (cfPWV).

Results: The mean age of the study population was 57.53 ± 9.34 years (139 women and 110 men). The mean duration of the disease was 10.2 years. The mean systolic blood pressure was at 138.9 ± 17.2 mmHg and the mean diastolic blood pressure was at 78.7 ± 9.8 mmHg. High blood pressure was found in 54.2% of the patients. Among them 33.3% had a controlled blood pressure under treatment. In this group, cfPWV was at 14.66 ± 2.83 m/s VS 12.43 ± 2.29 m/s in patients without hypertension (P < 0.001). Moreover, the presence of arterial stiffness multiples by 8 the risk of hypertension (Odds Ratio =8).

Conclusion: Both diabetes and hypertension are known to be causes for arterial stiffness and their association increases more this risk. Therefor a well-controlled blood pressure and glycemic level is necessary to slow down this process.

Volume 81

European Congress of Endocrinology 2022

Milan, Italy
21 May 2022 - 24 May 2022

European Society of Endocrinology 

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