ECE2022 Eposter Presentations Thyroid (219 abstracts)
Papillary thyroid carcinoma revealed by hyperthyroidism
Messaoudi Najoua 1 , Imane Assarrar 1 , Nisrine Bouichrat 1 , Marouan Karrou 1 , Siham Rouf 2 & Hanane Latrech 3
1Mohammed VI University Hospital Center, Faculty of Medecine and Pharmacy, University of Mohammed 1st, Department of Endocrinology-Diabetology and Nutrition, Oujda, Morocco; 2Faculty of Medicine and Pharmacy of Oujda, Mohamed the First University, Department of Endocrinology-Diabetology-Nutrition, Oujda, Morocco; 3Faculty of Medicine and Pharmacy of Oujda, Mohamed the First University, Department of Endocrinology-Diabetology-Nutrition, Laboratory of Epidemiology, Clinical Research and Public Health, Oujda, Morocco
Introduction: Papillary thyroid carcinoma is the most common histological type of differentiated thyroid malignancy. This type of tumor is rarely associated with thyroid hormone hypersecretion. We report the case of a patient with papillary thyroid carcinoma revealed by hyperthyroidism.
Case report: A 35 years old patient was admitted for the management of malignant hypercalcemia discovered incidentally on the biological workup performed preoperatively for a humerus fracture. The biological and radiological assessment revealed a primary hyperparathyroidism secondary to a parathyroid adenoma and hyperthyroidism secondary to a nodular goiter. TSH anti-receptor antibodies and calcitonin were negative. After obtaining normocalcemia and normalization of the thyroid assessment, the patient underwent a total thyroidectomy with a left parathyroid adenectomy. The anatomopathological study confirmed the presence a parathyroid adenoma without signs of malignancy, as for the thyroidectomy specimen, the histological study revealed a vesicular carcinoma with presence of a capsular effraction and vascular emboli, classified pT3aNxMx.
Conclusion: The association of thyroid cancer and hyperthyroidism is a rare event. Its pathogenesis remains poorly elucidated. Hyperthyroidism in these cases may be secondary to the primary carcinoma, as well as due to metastases, hence the importance of a complete extensive evaluation.
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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