Searchable abstracts of presentations at key conferences in endocrinology
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European Congress of Endocrinology 2022

Milan, Italy
21 May 2022 - 24 May 2022

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The 24th European Congress of Endocrinology (ECE) and the Italian Society of Endocrinology look forward to welcoming you to Milan. ECE 2022 returns for a four day, six parallel session festival of endocrine science. You can join us In person in Milan, Italy OR Live @Home online!

Symposia

Autoimmune polyendocrine syndromes

ea0081s21.1 | Autoimmune polyendocrine syndromes | ECE2022

Autoimmunity in families with Addison’s disease

Fichna Marta

Since individuals with autoimmune Addison’s disease (AD) present considerable co-occurrence of other autoimmune conditions, clustering of autoimmunity was also predicted among their relatives. We aimed to evaluate the burden of autoimmunity in families of patients with AD by means of a survey, serum autoantibody testing and correlating these data with the established genetic risk factors (PTPN22 rs2476601, CTLA4 rs231775, and BACH2 rs3757247). 7...

ea0081s21.3 | Autoimmune polyendocrine syndromes | ECE2022

Autoimmune regulator mutations and autoimmunity

Oftedal Bergithe

The autoimmune regulator (AIRE) gene is crucial for establishing central immunological tolerance and preventing autoimmunity. Mutations in AIRE cause a rare autosomal-recessive disease, autoimmune polyendocrine syndrome type 1 (APS-1). The clinical picture is highly variable, however, most patients present severe chronic mucocutaneous candidiasis and organ-specific autoimmunity from early childhood and have high levels of autoantibodies against interferon alpha and omega. Rece...