Searchable abstracts of presentations at key conferences in endocrinology
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European Congress of Endocrinology 2022

Milan, Italy
21 May 2022 - 24 May 2022

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The 24th European Congress of Endocrinology (ECE) and the Italian Society of Endocrinology look forward to welcoming you to Milan. ECE 2022 returns for a four day, six parallel session festival of endocrine science. You can join us In person in Milan, Italy OR Live @Home online!

Symposia

Organ crosstalk in metaflammation

ea0081s5.1 | Organ crosstalk in metaflammation | ECE2022

Beta cells and inflammation in diabetes

Mandrup-Poulsen Thomas

Innate immunity contributes to inducing functional inhibition and apoptosis of pancreatic beta-cells in the pathogenesis of both Type 1 diabetes (T1D) and Type 2 diabetes (T2D). The past four decades has provided overwhelming circumstantial evidence from in vitro studies and animal models that innate immune cells and cytokines are key effectors in beta-cell killing. Pro-inflammatory cytokines activate signaling pathways that reprogram the beta-cell transcriptome and proteome, ...