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Endocrine Abstracts (2022) 81 EP39 | DOI: 10.1530/endoabs.81.EP39

Farhat Hached University Hospital, Endocrinolgy, Sousse, Tunisia.


Introduction: Hypertension disorders during pregnancy constitute a significant cause of maternal and perinatal mortality worldwide. Paragangliomas represent a rare cause of hypertension in gestation. The management of these endocrine tumors can be challenging, especially when diagnosed during pregnancy. We describe a case of a paraganglioma discovered in a pregnant woman.

Case report: We report the case of a twenty-seven-year-old female patient who presented to our endocrinology department with gestational diabetes when she was 27 weeks pregnant. At 20 weeks of gestation, she was explored for high blood pressure, and the diagnosis of gestational hypertension was retained and treated with calcium inhibitors. The patient continued to have elevated blood pressure with typical signs of the Menard triad. A pheochromocytoma was then suspected. Plasma metanephrine levels were twelve times above the normal range. Since the patient was pregnant, MIBG scintigraphy could not be practiced. Thoracic and abdominal MRI showed a retroperitoneal and right latero-aortic mass of 3.5 cm. The diagnosis of paraganglioma was established, we treated the patient with alpha-blockers. As for her diabetes, she required insulin therapy. Surgical treatment was postponed. She had regular control of her hypertension and diabetes. The obstetrical ultrasound did not show any abnormalities during control. The patient had cesarean delivery at 38 weeks of gestation with a positive outcome.

Conclusion: Paraganglioma represents a rare cause of hypertension during pregnancy. The association between hypertension and diabetes should be alarming, especially during the first weeks of gestation. The early diagnosis of this situation can make its management less complicated.

Volume 81

European Congress of Endocrinology 2022

Milan, Italy
21 May 2022 - 24 May 2022

European Society of Endocrinology 

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