Endocrine Abstracts

Introduction: Oncocytic thyroid carcinoma is rare. It is an aggressive tumor, with high nodal and distant metastatic potential.

Purpose of the study: to describe the epidemiological, clinical and anatomopathological particularities of oncocytic carcinomas of the thyroid.

Method: Descriptive retrospective study, including patients followed in thyroid carcinoma consultation at the Endocrinology Department of the CHU Ibn Rochd in Casablanca from 1986 to 2021.

Results: we collected 12 cases of oncocytic carcinomas of the thyroid. The average age of the patients was 53.4 years with a female predominance (11women/1 man). The circumstance of discovery was a multiheteronodular goiter in 67% of the cases, a thyroid nodule in 25% and a toxic multinodular goiter in 8% of the cases. In our series, the majority of patients (67%) had nodules on ultrasound classified EU-TIRADS4. Treatment consisted of total thyroidectomy in 100% of patients, associated with cervical lymph node dissection in 17% of patients. The average size on the anatomopathological examination of these carcinomas was 4.4 cm; the multifocal character was objectified in 25% of the cases with an extrathyroid microscopic extension in 41.6% of the cases. All our patients subsequently benefited from radioactive iodine therapy.

Conclusion: Oncocytic carcinomas of the thyroid constituting a particular anatomo-clinical entity. The diagnosis is based on a range of clinical (size of the nodule, age over 50 years) and histological (capsular rupture, multifocality, angioinvasion) arguments. The surgery must be wide in front of the resistance to radioactive iodine therapy.