Searchable abstracts of presentations at key conferences in endocrinology
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Society for Endocrinology Endocrine Update 2022

Society for Endocrinology Clinical Update 2022

Workshop A: Disorders of the hypothalamus and pituitary

ea0082wa1 | Workshop A: Disorders of the hypothalamus and pituitary | SFEEU2022

Yet another case of Diabetes Insipidus!

Salema Valmiki , Velusamy Anand

26year old Human rights activist being evaluated for left hip and thigh pain over the preceding 7 months, was referred to our services in November 2015 with headache, secondary amenorrhoea and raised prolactin levels. The headache which was mainly frontal started a few months ago and coincided with the amenorrhoea. She did not report visual disturbances or lactation. She also described the feeling of increased thirst and increased urinary frequency over this period. Apart from...

ea0082wa2 | Workshop A: Disorders of the hypothalamus and pituitary | SFEEU2022

Lymphocytic hypophysitis in pregnancy

Subramaniam Yuvanaa , Waterhouse Mona

A 33-year-old woman who was 38-weeks pregnant was referred to our Endocrine team for bilateral temporal hemianopia. Her past medical history includes juvenile myoclonic epilepsy, for which she takes lamotrigine 275mg BD. She was reviewed by the Endocrinologist in 2018 for polyuria and nocturia which were attributed to the introduction of antiepileptics (normal pituitary biochemistry and MR pituitary). Her symptoms subsequently improved. Current symptoms started with acute retr...

ea0082wa3 | Workshop A: Disorders of the hypothalamus and pituitary | SFEEU2022

A case of pituitary apoplexy in a macroprolactinoma

Ying Khor Xiao , Kaushal Kalpana , Joseph Pappachan

A 32-year-old man was urgently referred to the endocrinology and neurosurgical teams by the neuro-ophthalmologist. He gave a 3 week history of sudden onset of left-sided visual impairment, with further visual deterioration a week previously. Urgent review in the eye clinic had revealed that the visual acuity in his left eye was reduced to finger counting only, with a pale left optic disc and a relative afferent pupillary defect on examination. Visual field testing demonstrated...

ea0082wa4 | Workshop A: Disorders of the hypothalamus and pituitary | SFEEU2022

Non-functioning pituitary adenoma with high Ki 67 10%

Rasool Irum , Murray Robert

A 54 year old gentleman presented to the eye services with reduced vision on the right attributed to a cataract. Following cataract surgery there was no improvement and his vision declined further with reducing vision also on the left. He was reviewed in Neuro-ophthalmology clinic 29/10/21 and clinical suspicion of a pituitary lesion based on binasal retinal ganglion cell layer loss and bilateral optic atrophy prompted urgent imaging. His right eye visual acuity was to hand mo...

ea0082wa5 | Workshop A: Disorders of the hypothalamus and pituitary | SFEEU2022

A case of recurring prolactinoma in pregnancy

Mathew Susan , Jude Edward

Background: Prolactinomas are the most common functioning pituitary tumours, accounting for 40% of all pituitary adenomas. Prolactinomas may enlarge in pregnancy, the management of which may prove challenging. Case Presentation: A 23 year old lady was referred to the endocrine clinic with secondary amenorrhoea and bifrontal headaches in 2012. Biochemical tests on referral revealed: FT4- 5.8 pmol/l, TSH-1.1 mU/l, Prolactin-4432 mIU/l, LH- 4.8 IU/l, FSH- 4...

ea0082wa6 | Workshop A: Disorders of the hypothalamus and pituitary | SFEEU2022

Pituitary function tests – Partial empty sella syndrome with panhypopituitarism

Ranasinghe Beatrice , Chhina Navpreet

Case history: 66 year old male referred with a thyrotoxic biochemistry. History was in favour of a subacute thyroiditis with a painful neck and short-term elevation of fT3 and fT4 which have improved to lower limits of normal without any treatment at the time of first clinic visit. He was monitored for thyroiditis and the biochemistry gradually changed and patient started to complain of tiredness. Investigations and treatment: Morning Pituitary profile i...

ea0082wa7 | Workshop A: Disorders of the hypothalamus and pituitary | SFEEU2022

Non-functioning granulomatous pituitary adenoma: Common pathology in an unlikely site

ZM Lim Jonathan , Purewal Tejpal , K Sinha Ajay , Grounds Kerrie , Sharma Dushyant

Background: Tuberculosis (TB) is an important cause of mortality and morbidity globally. Only a small proportion cases of systemic TB present with lesions spreading to meninges, sella, or ventricles. Cases of intra-sellar pituitary adenoma secondary to TB have been rarely identified, often with uncertainty on medical management as opposed to more aggressive surgical therapy. We report an interesting case of pituitary adenoma presenting with pan-hypopituitarism and posterior pi...

ea0082wa8 | Workshop A: Disorders of the hypothalamus and pituitary | SFEEU2022

Rapid enlargement of non-functioning pituitary adenoma during pregnancy and its spontaneous regression postpartum

Bhopal Sadaf , Farah George

33-year-old female presented at 35 weeks of pregnancy with black spots in the peripheral vision and headaches to Ophthalmology department. No other relevant clinical symptoms of note and no past medical history. On examination she had bitemporal hemianopia confirmed on perimetry hence was referred to Endocrine department. The MRI showed pituitary macroadenoma (1.8 cm x 2 cm x 1.2 cm), with extension into suprasellar and parasellar regions and displacement of the optic chiasm. ...

ea0082wa9 | Workshop A: Disorders of the hypothalamus and pituitary | SFEEU2022

Usefulness of desmopressin stimulation test in ACTH dependent Cushing’s syndrome in a young patient with no obvious pituitary lesion

Ali Mudassir , Ahmed Razi , Woods David , Mamoojee Yaasir

A 41 year-old male was referred urgently from secondary care with high suspicion of CushingÂ’s syndrome. His past medical history included psychosis and bipolar disorder, previous low impact foot fractures, rib fractures on coughing and spinal wedge fractures on X-ray, all within the last 5 years. He was taking quetiapine 300 mg modified-release and amitriptyline 10 mg daily, and tramadol 50 mg as needed. The patient reported decreasing mobility with increasing back pain, ...

ea0082wa10 | Workshop A: Disorders of the hypothalamus and pituitary | SFEEU2022

A case of Pituitary macroadenoma co-secreting TSH and GH complicated with pituitary apoplexy

Aye Thant Aye , Kearney Tara

Background: The plurihormonal pituitary adenomas represent 10-15% of all functioning pituitary adenoma. Mixed Growth hormone and prolactin secreting adenomas are the commonest one, approximately 5% of surgically removed adenoma. Other hormonal mixture of adenoma may occur, but very rare. We present a rare case of co-secreting TSH and GH adenoma. Clinical Case: A 45 year old gentleman, generally fit and well, presented with 3 years history of blurred visi...

ea0082wa11 | Workshop A: Disorders of the hypothalamus and pituitary | SFEEU2022

A case of lymphocytic hypophysitis presenting with diabetes insipidus

Gaur Smriti , Aboul Hossn Tamara , Morris Damian

Introduction: Lymphocytic hypophysitis(LH) is a rare autoimmune endocrinopathy that causes pituitary gland inflammation, resulting in hypopituitarism. Headache is the most common presenting symptom; however, diabetes insipidus (DI) may be the first feature in some patients. Here we report one such case. Case: a 36-year-old female was referred to the Endocrine clinic with sudden onset of polydipsia, polyuria and nocturia. She also reported amenorrhoea but...

ea0082wa12 | Workshop A: Disorders of the hypothalamus and pituitary | SFEEU2022

Pituitary functions and Hypothalamic Pituitary Axis Assessment Post Pituitary Surgery

Naeem Ammara , Baldeweg Stephanie

47 year old gentleman referred to Neurosurgery Department with incidental findings of pituitary macroadenoma with chiasmal compression and cavernous sinus involvement, whilst getting investigated for tinnitus. His past medical history included chronic migraines only. He has been experiencing increased frequency of migraines along with lethargy, decreased libido and loss of morning erections for some time prior to presentation. His formal visual fields showed a slight inferior ...