Searchable abstracts of presentations at key conferences in endocrinology
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Society for Endocrinology Endocrine Update 2022

Society for Endocrinology Clinical Update 2022

Workshop C: Disorders of the thyroid gland

ea0082wc1 | Workshop C: Disorders of the thyroid gland | SFEEU2022

Subclinical hyperthyroidism and its many facets; a presentation with severe thyroid eye disease

Shepherd Carol , Muralidhara Koteshwara , Kyaw Ye

Case History: A 70-year-old man of Chinese origin presents with a two-month history of worsening visual acuity and double vision. He denied systemic symptoms apart from marginal weight loss. Other medical history includes stable asthma, treated with inhalers. He has a niece and nephew with thyroid disease. He is an ex-smoker, retired accountant, and drinks occasional alcohol. On examination, he was normotensive with a body mass index of 22 kg/m2 however was found to...

ea0082wc2 | Workshop C: Disorders of the thyroid gland | SFEEU2022

Thyroid function tests - Thyroid hormone resistance

Ranasinghe Beatrice , Chhina Navpreet

Case history: 61 year old female with a history of inherited dilated cardiomyopathy was referred with abnormal thyroid functions not improving with Levothyroxine. She has been on Levothyroxine 100 mg which she has discontinued 5 months prior to the review but her thyroid function abnormality persisted. She had no family history of thyroid abnormalities.Investigations: Negative TSH receptor antibodies.Treatment and follow up:<table boarder="1" cellpad...

ea0082wc3 | Workshop C: Disorders of the thyroid gland | SFEEU2022

Familial dysalbuminaemic hyperthyroxinaemia as a cause of discordant thyroid function tests

Klaucane Katarina , Krishnan Amutha , Vamvakopoulos Joannis

Introduction: Discordant thyroid function tests are frequently identified in clinical practice and should raise suspicions about laboratory analytical interference.Case report: A 59 year old male was referred to Endocrine services for abnormal thyroid function tests following his recent Emergency department presentation with palpitations. His TFT (Roche) showed FT4 level was raised at 27.1 pmol/l (6.5 - 17.0), and his TSH normal at 2.57 uIU/ml (0.34 - 5....

ea0082wc4 | Workshop C: Disorders of the thyroid gland | SFEEU2022

A grave interference: TSH interference due to macro-TSH post-thyroidectomy for graves” disease

McCarthy Aisling , Moran Carla

A 26 year old gentleman presented to his GP in July 2018 with a one month history of thyrotoxic symptoms, including palpitations and weight loss. His initial thyroid function tests (TFTs) showed a hyperthyroid picture, including a FT4 of >100pmol/l (RR 12-22). His TSH receptor antibody was 11.1 IU/l (RR <1.75). He had no evidence of thyroid eye disease, and no goitre or thyroid nodules on exam. His Graves” disease was initially managed medically with carbimazole. ...

ea0082wc5 | Workshop C: Disorders of the thyroid gland | SFEEU2022

Two case reports of suspected thyroid assay interference

Miler Emma , Chipchase Allison , Ahluwalia Rupa

Case 1: A 17-year-old female was referred to the endocrinology outpatients due to abnormal thyroid function tests (TFTs) (as below) detected on routine monitoring for Thyroxine replacement therapy. Following exclusion of pregnancy, possibilities of assay interference due to heterophilic antibodies as well as thyroid hormone resistance were considered. Repeat analysis was arranged at two laboratories using different methods. Results were concordant, excluding assay interference...