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Endocrine Abstracts (2022) 83 DOMNO6 | DOI: 10.1530/endoabs.83.DOMNO6

1Dubrava Clinical Hospital, Department of Endocrinology, Diabetes, Metabolic Diseases and Clinical Pharmacology; 2Dubrava Clinical Hospital, Department of Abdominal Surgery; 3Dubrava Clinical Hospital, Nutrition Department

Background: According to the World Health Organization, there are approximately 650 million obese adults worldwide. In Croatia almost 2/3 (65%) of adults are overweight (42%) or obese (23%), with a growing tendency both in adults and children. The surgical procedures performed to manage obesity are referred to as metabolic or “bariatric” surgery. Candidates for a bariatric surgical procedure include obese patients with a BMI ≥ 40 kg/m2(obesity class III) or ≥ 35 kg/m2(obesity class II) and the presence of comorbidities related to obesity.

Objectives: To assess the effect of bariatric surgery on anthropometric analysis and metabolic laboratory parameters in adults with obesity in a single-centre in Zagreb, Croatia.

Methods: We retrospectively examined the medical records of patients aged 18 years or older, who were admitted for sleeve gastrectomy procedure to Clinical Hospital Dubrava, Zagreb, Croatia, between October 2015 and March 2022. Clinical and demographic data and comorbidities of interest were recorded. The patients underwent a standard and additional set of blood tests and anthropometric analysis. For 30 patients who were followed-up in the outpatient clinic we investigated long-term outcomes.

Results: A total of 41 patients (82.9% female) with the mean age of 44.80 ± 9.7 years underwent the surgery. The mean pre-surgery weight was 134.56 ± 22 kg, with a BMI of 47.57 ± 7.21 kg/m2. In the mean period of surgery follow-up (76 days) there was a significant weight loss of 19.07 kg (P < 0.001) with a BMI reduction of 5.61 kg/m2 (P < 0.001) and a significant reduction in the mass of body fat (MBF) and the visceral adiposity index (VAI). The median reduction in HbA1c was 0.64% (P < 0.001) averagely 76 days after surgery.

Conclusions: Bariatric surgery is associated with a fast and significant improvement of anthropometric and metabolic parameters, being among the most effective management modalities for patients with obesity.

Volume 83

ESE Young Endocrinologists and Scientists (EYES) 2022

Zagreb, Croatia
02 Sep 2022 - 04 Sep 2022

European Society of Endocrinology 

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