EYES2022 ESE Young Endocrinologists and Scientists (EYES) 2022 Reproductive and Developmental Endocrinology (13 abstracts)
Effects of COVID-19 on menstrual cycle changes in women with polycystic ovary syndrome
Petković D 1 , Marina Lj. 1,2 , Dugić B 3 , Saravinovska K 1 , Šojat A. S. 2 , Rosić N 1 , Petković T 2 , Antić N 2 , Ristović N 1 , Ivović M. 1,2 , Tančić-Gajić M 1,2 , Arizanović Z 2 & Vujović S. 1,2
1University of Belgrade, Faculty of Medicine; 2 Clinic for Endocrinology, Diabetes and Metabolic Diseases, University Clinical Centre of Serbia, National Centre for Infertility and Endocrinology of Gender; 3 University of Belgrade, School of Electrical Engineering
Background: It was shown that women with polycystic ovary syndrome (PCOS) are at an increased risk of COVID-19. However, it is not known whether COVID-19 has any effects on reproductive health of PCOS patients.
Objectives: Aim of the study was to evaluate possible effects of COVID-19 on reproductive health in patients with PCOS.
Methods: An anonymous survey about reproductive health was conducted in PCOS patients and healthy control (HC).
Results: 254 women completed the survey. All women reported recording their cycles using a phone application. After exclusion of women who had negative COVID- 19 test, incomplete survey data and women in menopause, our cohort consisted of 133 females with confirmed COVID-19 prior to evaluation, 30 with PCOS and 103 HC patients. Mean age of patients was 30.09 ± 9.76 years and BMI 22.64 ± 3.5 kg/m2. Patients with PCOS reported significantly higher changes in menstrual cycle characteristics than HC (P < 0.05). Most noted changes were missed periods, heavier flow and more painful bleeding. Namely, women with PCOS had significantly shorter duration of menstrual bleeding in comparison with HC (P < 0.05). There was no difference in changes in PMS symptoms, frequency of period and menstrual flow between groups.
Conclusion: COVID-19 has significant effects on already vulnerable reproductive health of PCOS patients. The exact mechanism why COVID-19 has these effects remains to be elucidated.
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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