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44th Annual Meeting of the European Thyroid Association (ETA) 2022

Brussels, Belgium
10 Sep 2022 - 13 Sep 2022

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Poster Presentations

Pregnancy & Iodine

ea0084ps3-13-114 | Pregnancy & Iodine | ETA2022

The troubled discourse of hypothyroidism in pregnancy: sentiment analysis of the literature from 2011 to 2021

Ilias Ioannis , Milionis Charalampos , Venaki Evangelia , Koukkou Eftychia

Introduction/Aim: The diagnosis and management of hypothyroidism in pregnancy is a domain of shifting paradigms, with changes in guidelines, which may have led clinicians to confusion or angst (Endocrine Today; October 2019). Since sentiment analysis (SA) of medical texts can be implemented (Artificial Intelligence in Medicine 2015; 64: 17–27) we sought to use SA regarding this clinical issue.Materials/Methods: We collected the English language abst...

ea0084ps3-13-115 | Pregnancy & Iodine | ETA2022

Higher thyroid FT3-to-FT4 ratio is associated with gestational diabetes mellitus and adverse pregnancy outcomes

Raets Lore , Minschart Caro , Van Den Bruel Annick , Van en Bogaert Emmelien , Van Crombrugge Paul , Moyson Carolien , Verhaeghe Johan , Vandeginste Sofie , Verlaenen Hilde , Vercammen Chris , Maes Toon , Dufraimont Els , Roggen Nele , De Block Christophe , Jacquemyn Yves , Mekahli Farah , De Clippel Katrien , Loccufier Anne , Laenen Annouschka , Devlieger Roland , Mathieu Chantal , Decallonne Brigitte , Benhalima Katrien

Aim: To determine the association between thyroid function and the risk for gestational diabetes mellitus (GDM) and adverse pregnancy outcomes.Methods: This case-control study was a sub-analysis of the BEDIP-N study, in which 199 GDM women were matched for age and body mass index with 398 controls. Thyroid stimulating hormone (TSH), free thyroxine (fT4), free triiodothyronine (fT3), and thyroid peroxidase (TPO) antibodies were measured at 6-14 weeks and ...

ea0084ps3-13-116 | Pregnancy & Iodine | ETA2022

Iodine status in danish pregnant women after an increase in iodine fortification: a regional study

Knosgaard Louise , Andersen Stig , Bo Hansen Annebirthe , Nodgaard Sorensen Anne , Vestergaard Peter , Linding Andersen Stine

Objectives: The Danish population was previously iodine deficient with regional differences, and a mandatory iodine fortification of salt was introduced more than 20 years ago. Despite iodine fortification and frequent use of iodine-containing supplements, the iodine status in Danish pregnant women was insufficient when evaluated in 2012 (median urinary iodine concentration (UIC): 101 µg/l). From July 1, 2019 the authorities implemented a mandatory increase from 13 to 20 ...

ea0084ps3-13-117 | Pregnancy & Iodine | ETA2022

Iodine status during pregnancy in the veneto region: impact on maternal and newborn thyroid function and analysis of the nutritional and socio-economic determinants

Censi Simona , Mondin Alberto , Messina Giulia , Pedron Mariachiara , Manso Jacopo , Faggian Diego , Basso Daniela , Bertazza Loris , Barollo Susi , Marin Loris , Camilot Marta , Andrisani Alessandra , Mian Caterina

Objectives: The aim was to evaluate the iodine nutritional status in pregnant women residing in Veneto region and its associations with diet, iodine supplements and social status (nationality and education).Methods: 292 consecutive pregnant women at the third trimester of pregnancy were enrolled (≥18 years old, and resident in Veneto). Exclusion criteria were a personal history of thyroid disease and the refusal of the informed consent. Every woman...

ea0084ps3-13-118 | Pregnancy & Iodine | ETA2022

Which is the best pre-conceptional TSH cut-off in women submitted to assisted reproductive technology?

Vannucchi Guia , Campi Irene , Cagnina Serena , Covelli Danila , Mignini Renzini Mario , Persani Luca , Fugazzola Laura

TSH is involved in the immunomodulation of early pregnancy stages. Thyroid guidelines have indicated 2.5 mU/l as the best TSH level below which women undergoing assisted reproductive technology (ART) need to be maintained, though this treshold is still controversial. Aims of the present study were to evaluate if pre-conceptional TSH is associated with an increased risk of miscarriage, to identify a TSH cut-off significantly associated with risk of miscarriage and to assess the...

ea0084ps3-13-119 | Pregnancy & Iodine | ETA2022

The impact of iodine supplementation in pregnancy on iodine intake, thyroid function and thyroid volume in pregnant women from iodine sufficient region

Gladic Nenadic Vedrana , Blazekovic Ivan , Bosak Butkovic Marija , Jaksic Ivan , Kusic Zvonko , Jukic Tomislav

Objective: The aim of the study was to assess the impact of iodine supplementation (IS) on iodine intake, thyroid function and thyroid volume (Tvol) in pregnant women (PW) from iodine sufficient region of Zagreb, the capital of Croatia. The secondary aim was to asses the impact of nodular or diffuse thyroid ultrasound (US) pattern on serum thyroglobulin (Tg) measurement.Subjects and Methods: The study enrolled 91 PW taking IS (onIS) and 100 PW without IS...

ea0084ps3-13-120 | Pregnancy & Iodine | ETA2022

The impact of thyroid function on neonatal outcome in women with polycystic ovary syndrome treated with metformin or placebo during pregnancy

Trouva Anastasia , Alvarsson Michael , Calissendorff Jan , Olav AEsvold Bjorn , Linden Hirschberg Angelica , Vanky Eszter

Objectives: Polycystic ovary syndrome (PCOS) and thyroid disorders have separately been linked to adverse pregnancy and neonatal outcomes. Even small variations in thyroid function within the normal range may influence fetal growth. Previous data have shown that metformin-treatment of pregnant women with PCOS reduced late miscarriages and preterm births, and resulted in less decrease of fT4 compared to placebo. Moreover, metformin exposure in utero altered the offspring anthro...

ea0084ps3-13-121 | Pregnancy & Iodine | ETA2022

Thyroid homeostasis in iodine deficient healthy pregnant women from 10 villages of bihar, india

Chandola Asha

Background: Pregnancy is a physiological state characterised by enhanced thyroid hormone production resulting in increased demand for iodine. Iodine deficiency during pregnancy, is therefore, considered to be a risk factor for adequate growth and development in offspring. However our understanding of thyroid hormone homeostasis in iodine deficient environment is limited.Objectives: 1)To assess the current iodine status in pregnant women from an endemic z...

ea0084ps3-13-122 | Pregnancy & Iodine | ETA2022

Preconception tsh levels and early gestation maternal thyroid function in a large cohort of women with hashimoto’s thyroiditis (ht) diagnosed preconceptionally

Moleti Mariacarla , Di Mauro Maria , Paola Giuseppe , Perdichizzi Laura , Ragonese Marta , Granese Roberta , Alibrandi Angela , Vermiglio Francesco

Several lines of evidence indicate an increased risk of adverse gestational outcomes in women with Hashimoto’s thyroiditis (HT) already as of TSH levels at early pregnancy >2.5mU/l, and definitely greater for TSH concentration >4mU/l. The latest guidelines recommend preconception TSH levels (pre-C-TSH) in HT women be maintained below 2.5mU/l, this threshold being expected to prevent hypothyroidism occurrence at early gestation.Objectives: To...