ea0085nep2.1 | Endocrine Symposium 4 | BSPED2022
, Tobin Laura
, O'Shea Donal
, Cody Declan
, Hogan Andrew
Obesity is linked to an increased risk of 13 different cancers in adulthood. The environment supporting this increased risk is multi-factorial but includes metabolic dysregulation, chronic inflammation and the loss of the anti-tumour activity of cells such natural killer (NK) cells. We present data which shows that this pro-cancer environment starts early in children with obesity, potentially increasing their risk of future disease. We investigated a cohort of 50 children with...