Endocrine Abstracts

Pseudohypoaldosteronism is a rare salt-wasting disorder of infancy characterised by hyponatraemia, hyperkalaemia and metabolic acidosis, with increased plasma renin activity and elevated aldosterone concentrations (1). We present three recent cases.Case 1: An 8 day old female infant presented with poor feeding and vomiting. She was born to consanguineous parents. She was bradycardic, hypothermic and clinically shocked. Initial bloods showed hyponatraemia...

Case report: A previously well 16 year old female presented with a one day history of being unwell with agitation and confusion on the background of a three month history of polydipsia and polyuria. Initial biochemistry was in keeping with severe diabetic ketoacidosis (DKA): pH-6.75, HC03- 2.6 mmol/l, blood glucose- 21 mmol/l and ketones >4 mmol/l. Hypokalaemia of 3.3 mmol/l. She was admitted to ICU given the severity of DKA, biochemical disturbance and altered mental stat...