Endocrine Abstracts

Since reports published in 2015 and 2016 identified 15 probable exposure-outcome associations due to endocrine-disrupting chemicals (EDCs), new studies in humans has now deepened understanding of their effects on human health. Particularly stronghas emerged for relations between perfluoroalkyl substances and child and adult obesity, impaired glucose tolerance, gestational diabetes, reduced birthweight, reduced semen quality, polycystic ovarian syndrome, endometriosis, and brea...

Abstract Unavailable...

Environmental endocrine-disrupting chemicals (EDCs) are exogenous chemicals that perturb hormones and their actions. In our laboratory, we are studying how early life exposures to EDCs affect the developing brain and lead to behavioral dysfunctions in exposed individuals and their descendants across generations. To do this, pregnant rats are fed one of three treatments: the weakly estrogenic commercial polychlorinated biphenyl (PCB) mixture, Aroclor 1221 (A1221, 1 mg/kg); vinc...