Searchable abstracts of presentations at key conferences in endocrinology
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Society for Endocrinology BES 2022

Harrogate, United Kingdom
14 Nov 2022 - 16 Nov 2022

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SfE BES is returning to Harrogate in 2022. Join with endocrine specialists from across the UK and beyond for the Society for Endocrinology's flagship meeting.

Early Career and Plenary Orals

Early Career Prize Lecture Clinical

ea0086ec1.2 | Early Career Prize Lecture Clinical | SFEBES2022

Central adiposity raises serum calcium concentrations and increases risk of kidney stone disease

Lovegrove Catherine , Besevic Jelena , Wiberg Akira , Lacey Ben , Littlejohns Thomas , Allen Naomi , Goldsworthy Michelle , Kim Jihye , Hannan Fadil , Curhan Gary , Turney Ben , McCarthy Mark , Mahajan Anubja , Thakker Rajesh , Holmes Michael , Furniss Dominic , Howles Sarah

Background: Kidney stone disease (KSD) has been linked to obesity, metabolic syndrome and higher serum calcium concentration (SCa). The mechanisms underlying these associations are uncertain. Using conventional and genetic epidemiological techniques, we aimed to investigate the effects of adiposity on KSD.Methods: Observational associations between adiposity and incident KSD in 479, 405 people from the UK Biobank were assessed. Genome-wide association st...