Endocrine Abstracts

Abstract Unavailable...

Patients with low-risk thyroid cancer are at risk for overtreatment. Autopsy studies and survival statistics suggest that many patients with thyroid cancer have indolent disease that is unlikely to lead to death. Prior studies have found similar long-term outcomes with less intensive management. Yet, there remains marked variation in care, with some patients at risk for overtreatment. Data from large cancer registries, as well as patient report, provide evidence that overtreat...

An increased understanding of the genetic changes leading to thyroid cancers in recent years has led to a rapid increase in the number of effective targeted systemic therapies available for patients with advanced thyroid cancer. The multi-kinase inhibitors were the first drugs to show significant benefit but more recently more specific inhibitors of RET, BRAF, MEK and NTRK have been developed and are showing great promise. In this session I will discuss this paradigm shift in ...