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Endocrine Abstracts (2022) 86 P223 | DOI: 10.1530/endoabs.86.P223

SFEBES2022 Poster Presentations Metabolism, Obesity and Diabetes (96 abstracts)

Micronutrient concentrations and their associations with BMI in bariatric surgery patients

Victoria Ramsbottom 1,2 & Akheel Syed 1,2

1Diabetes and Endocrinology, Salford Royal Foundation Trust, Manchester, United Kingdom; 2University of Manchester, Manchester, United Kingdom

Purpose: Obesity and/or bariatric surgery can be associated with micronutrient deficiencies. We studied whether there was a correlation between body mass index (BMI) and micronutrient levels pre- and post-bariatric surgery.

Methods: We performed a retrospective cohort study of 745 patients who underwent bariatric surgery in a Northwest England teaching hospital. Patients were recommended standard postoperative supplements consistent with national guidelines. Data on concentrations of folate, iron, vitamin B12 and vitamin D and BMI were collected from electronic patient records before surgery and at 4-,12-,24-,36- and 48-months of follow-up.

Results: The patients included 514 (69.0%) women; 496 (66.6%) underwent gastric bypass, 240 (32.2%) sleeve gastrectomy and 10 (1.3%) gastric band surgery. At baseline, mean±SD age was 47.0±10.5 years, weight 135.1±23.6 kg and BMI 51.2±7.7 kg/m2; folate was 8.0±3.9 µg/l, iron 12.2±4.6 µmol/l, vitamin B12 411.4±269.1 ng/l and vitamin D 32.6±24.1 nmol/l. BMI at baseline was inversely correlated with serum folate (coefficient, -0.221) and vitamin D (-0.269), and weakly correlated with vitamin B12 (-0.069) and iron (-0.077) concentrations Mean concentrations of folate, iron, vitamin B12 and vitamin D increased with supplementation at follow-up.

12 months24 months48 months
Folate (µg/l)12.2812.8313.15
Iron (µmol/l)14.8015.1413.90
Vitamin B12 (ng/l)638.76691.90711.97
Vitamin D (nmol/l)52.2856.8253.75

Conclusion: The continued increase in micronutrient concentration and weakening negative correlation found between BMI, folate and vitamin D after follow-up appointments indicates the effectiveness of micronutrient supplementation. Investigations into the effect of other variables on micronutrient concentrations post-bariatric surgery are necessary to comprehend the BMI–micronutrient relationship further.

Table of mean micronutrient concentration before bariatric surgery at follow-up.

Volume 86

Society for Endocrinology BES 2022

Harrogate, United Kingdom
14 Nov 2022 - 16 Nov 2022

Society for Endocrinology 

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