Glucose and sodium levels as disease outcome predictors in critically ill patients

Tatjana Bačun; Željka Dragila; Andrea Dorokazi; Ivan Lekić; Damir Mihić; Domagoj Loinjak; Miroslav Šram

doi:10.1530/endoabs.90.EP294

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Endocrine Abstracts (2023) 90 EP294 | DOI: 10.1530/endoabs.90.EP294

ECE2023 Eposter Presentations Diabetes, Obesity, Metabolism and Nutrition (355 abstracts)

Glucose and sodium levels as disease outcome predictors in critically ill patients

Tatjana Bačun ^1,2 , Željka Dragila ² , Andrea Dorokazi ³ , Ivan Lekić ^1,4 , Damir Mihić ^1,2 , Domagoj Loinjak ^1,2 & Miroslav Šram ²

Err

Author affiliations

¹Faculty of Medicine, Osijek, Croatia; ²Clinical Medical Center Osijek, Osijek, Croatia; ³Poliklinika Slavonija, Osijek, Croatia; ⁴Dom Zdravlja Zagreb - Centar, Zagreb, Croatia

Aim: The main aim of this study was to examine the association of glucose and sodium level with diagnosis and disease outcome of critically ill patients.

Patients and Methods: The glucose and sodium concentration of 283 patients admitted in critical condition to the Intensive Care Unit of the Department of Internal Medicine in a period from 1 November 2015 to 28 February 2017 were reviewed.

Results: Most common diagnoses in critically ill patients were acute kidney injury (26.1%) and sepsis (including septic shock) (22.3%). Significantly lower glucose concentration was observed in patients with acute kidney injury (P=0.02), whereas patients in sepsis and septic shock had significantly higher sodium concentration (P=0.04). Higher glucose level was related to higher mortality rate (P=0.001). On the other hand, sodium level was not significantly associated with survival. Higher mortality as well as higher glucose concentration were more common in patients older than 65 years (P< 0.001).

Conclusion: This study has shown significantly lower concentrations of glucose in patients with acute kidny injury, whereas in patients older than 65, glucose concentration was significantly higher. Patients in sepsis and in septic shock have shown significantly higher concentrations of sodium. Higher concentration of glucose was connected with higher mortality in elders, where as concentration of sodium did not show connection with morality.

Keywords: critical illness; glucose; intensive care unit; sodium