Endocrine Abstracts

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Topical steroids are widely used by dermatologists and other physicians for the treatment of skin diseases such as diaper dermatitis. Iatrogenic Cushing syndrome may occur as an undesirable outcome of high-dose glucocorticoids treatments. This may also cause hypothalamus–hypophysis– adrenal axis suppression. While this situation may be caused more frequently with oral and topical glucocorticoid therapy, iatrogenic. Here, we report a 6 month-old boy with Cushing syn...

BackgroundBlack and African patients with type 2 diabetes have a greater frequency and more severe complications of the disease, even after correction for associated factors. Asymptomatic sickle cell trait (SCT; hemoglobin AS) is also common among black Africans and may independently cause endothelial damage, manifested as isolated target organ complications or infarction. We examined the possibility that patients with concurrent type 2 diabetes and SCT ...

BackgroundBlack and African patients with type 2 diabetes have a greater frequency and more severe complications of the disease, even after correction for associated factors. Asymptomatic sickle cell trait (SCT; hemoglobin AS) is also common among black Africans and may independently cause endothelial damage, manifested as isolated target organ complications or infarction. We examined the possibility that patients with concurrent type 2 diabetes and SCT ...

Objectives: Pheochromocytomas are rare neuroendocrine tumors that originate in chromaffin cells of the adrenal medulla and excessively secrete catecholamines, which leads to a multitude of different symptoms. The most common symptoms include headaches, palpitations and sweating. Because of a diverse clinical picture, they pose a major challenge in diagnostics and often go unidentified. The diagnosis is confirmed by measuring plasma and 24-hour urinary metanephrine and normetan...

Background: Human immunodeficiency virus (HIV) infection and the Acquired Immune Deficiency Syndrome (AIDS) are health problems with infected individuals frequently manifesting some abnormalities including significant weight loss. This has been associated withtumor necrosis factor alpha and interleukin 1β production by circulating mononuclear white blood cells in patients with HIV infection andaltered metabolism due to cytokine dysregulation and metabolic demands of antir...

Background: Human immunodeficiency virus (HIV) infection and the Acquired Immune Deficiency Syndrome (AIDS) are health problems with infected individuals frequently manifesting some abnormalities including significant weight loss. This has been associated withtumor necrosis factor alpha and interleukin 1β production by circulating mononuclear white blood cells in patients with HIV infection andaltered metabolism due to cytokine dysregulation and metabolic demands of antir...

A 35-year-old woman was seen at the medical obstetric antenatal clinic with gestational diabetes (GDM) and new-onset hypertension during the second trimester of her first pregnancy. She was well, with no prior medical history. Blood pressure of 120/80 had been recorded at her first antenatal visit. Throughout the pregnancy, GDM was managed successfully with diet alone: HbA1c always <5.8%. Methyldopa was initiated for persistent hypertension at 18 weeks gestation, and labet...

Aim of the study: The objectives of this study were to determine the regulation of glycemia (measured by fasting glucose levels and HbA1c) in patients with type 2 diabetes and to examine whether there is a difference in therapy (oral antidiabetics, insulin, combination), age, sex and BMI.Study design: Cross-sectional research with historical data.Patients: The study included 102 patients of both sexes (56% women and 44% men) with a...

Background: Type 1 diabetes mellitus (T1DM) is caused by destruction of pancreatic beta cells. Children and adolescents with type 1 diabetes have an increased risk of developing other autoimmune diseases, most commonly autoimmune thyroiditis and celiac disease.Objectives: To examine the frequency of individual human leukocyte antigen (HLA) alleles in people with T1DM and associated autoimmune (AI) diseases of the thyroid, digestive system, and skin, and ...