Searchable abstracts of presentations at key conferences in endocrinology
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25th European Congress of Endocrinology

Istanbul, Turkey
13 May 2023 - 16 May 2023

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ECE 2023 will be held in Istanbul, Turkey from 13-16 May 2023. Istanbul is known for its rich culture, historical sites and dynamic nightlife, and we are excited to come together in this city, and look forward to meeting old friends, making new ones, and sharing science, collaborations and ideas.

Oral Communications

Oral Communications 1: Diabetes, Obesity, Metabolism and Nutrition 1

ea0090oc1.1 | Oral Communications 1: Diabetes, Obesity, Metabolism and Nutrition 1 | ECE2023

Fish oil supplementation during pregnancy attenuates sex-specific changes induced by perinatal maternal high-fat diet in mitochondria of rat skeletal muscle at weaning

Woyames Juliana , Martins Isabela , Souza Manuella , Neto Jessika Oliveira , Andrade Cherley , Atella Georgia , Trevenzoli Isis , Moura Carmen Pazos

Perinatal maternal high-fat (HF) and isocaloric diet induced obesity and metabolic disorders in the offspring since weaning. At adulthood, oxidative soleus skeletal muscle of HF male offspring exhibited lipid accumulation and mitochondrial damage. At birth, HF offspring have higher n-6:n-3 polyunsaturated fatty acids (PUFA) plasma ratio. We hypothesized that HF offspring´s mitochondria of skeletal muscle exhibit damages at weaning that could be mitigated by fish oil (FO, ...

ea0090oc1.2 | Oral Communications 1: Diabetes, Obesity, Metabolism and Nutrition 1 | ECE2023

Semaglutide alters tongue transcriptome along with the improvement of taste perception and increased brain activation in response to sweet tasting solution in obese women with PCOS

Jensterle Mojca , Vovk Andrej , Kovac Jernej , Battelino Saba , Ferjan Simona , Hrast Barbara , Battelino Tadej , Janez Andrej

Background: Obese individuals may perceive the taste of caloric dense food as less intense, resulting in decreased activation of the reward system. Preclinical research provides some insights into the role of GLP-1 in the gustatory coding. The impact of GLP-1 receptor agonists on the tongue and taste perception remains largely unaddressed in clinical settings.Aim: to investigate the impact of semaglutide on the tongue transcriptome, taste perception and ...

ea0090oc1.3 | Oral Communications 1: Diabetes, Obesity, Metabolism and Nutrition 1 | ECE2023

Neuronostatin receptor GPR107 as a potential biomarker and therapeutic target in chronic liver disease

Garcia-Estrada Antonio , Herman-Sanchez Natalia , Lopez-Canovas Juan Luis , Saez-Martinez Prudencio , Zamora-Olaya Javier M , Rodriguez-Peralvarez Manuel , Luque Raul M , Gahete Manuel D.

Metabolic associated fatty liver disease (MAFLD) is rapidly becoming a major aetiology for the development of hepatocellular carcinoma (HCC, the most common liver cancer) in the context of chronic liver disease. Current therapeutical options for MAFLD (dietetic/lifestyle intervention and/or pharmacological approaches) are still insufficient and the cellular and molecular mechanisms underlying this disease are yet to be fully understood. Our group previously reported that the n...

ea0090oc1.4 | Oral Communications 1: Diabetes, Obesity, Metabolism and Nutrition 1 | ECE2023

Associations between handgrip strength and skeletal muscle mass with all-cause mortality and cardiovascular mortality: a prospective cohort study of UK Biobank

Zeng Jingjing , Wei Linqi , Chen Bo , Fan Menglin , Xu Shaoyong

Background: Handgrip strength (HGS) and skeletal muscle mass (SMM) are associated with all-cause and cardiovascular disease (CVD)-specific mortality risk in type 2 diabetes (T2DM) patients. However, the pattern of this association was unclear. We aimed to explore the pattern of associations between HGS and SMM with all-cause and CVD mortality risk in a diabetic population.Method: Data were obtained from the UK Biobank (application number 92014), a large ...