Searchable abstracts of presentations at key conferences in endocrinology
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25th European Congress of Endocrinology

Istanbul, Turkey
13 May 2023 - 16 May 2023

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ECE 2023 will be held in Istanbul, Turkey from 13-16 May 2023. Istanbul is known for its rich culture, historical sites and dynamic nightlife, and we are excited to come together in this city, and look forward to meeting old friends, making new ones, and sharing science, collaborations and ideas.


Spotlight on posterior pituitary

ea0090s1.2 | Spotlight on posterior pituitary | ECE2023

Are patients with diabetes insipidus oxytocin deficient?

Atila Cihan

Arginine vasopressin (AVP) and oxytocin (OXT) are neuropeptides produced in hypothalamic nuclei and released into circulation from axon terminals projecting to the posterior pituitary. A disrupted hypothalamic-pituitary axis caused by inflammation, tumours, or head trauma can cause AVP deficiency, also known as central diabetes insipidus (cDI), a condition characterised by polyuria and consecutive polydipsia. Once diagnosed, desmopressin, a selective AVP receptor 2 agonist, is...

ea0090s1.3 | Spotlight on posterior pituitary | ECE2023

Tolvaptan for hyponatremia in cancer

Peri Alessandro

Hyponatremia is the most common electrolyte disorder in hospitalized patients, including cancer patients. Multiple causes can lead to hyponatremia, but frequently this electrolyte disorder is due to the syndrome of inappropriate antidiuresis (SIAD). In cancer patients this syndrome is mostly secondary to ectopic secretion of arginine vasopressin by tumoral cells. In addition, several chemotherapeutic drugs induce the release of arginine vasopressin by the hypothalamus. There i...