ECE2023 Eposter Presentations Diabetes, Obesity, Metabolism and Nutrition (355 abstracts)
Dynamics of HbA1c and glycemia in OGTT during pregnancy in healthy women
Violeta Mladenovic 1,2 , Marija Andjelkovic 2,3 , Zoran Gluvic 4,5 & Milena Mitrovic 6,7
1University Clinical Center «Kragujevac», Serbia, Clinic for endocrinology, Diabetes and Metabolic Diseases, Kragujevac, Serbia; 2Faculty of Medical Sciences, Univeristy of Kragujevac», Serbia, Kragujevac, Serbia; 3University Clinical Center «Kragujevac», Serbia, Department of Laboratory Diagnostics, Kragujevac, Serbia; 4Zemun Clinical Hospital Center, Division of Internal Medicine, Dept of Endocrinology, Beograd, Serbia; 5School of Medicine, University of Belgrade, Serbia, Beograd, Serbia; 6University Clinical Center Vojvodina, Novi Sad, Serbia, Clinic for Endocrinology, Diabetes and Metabolic Diseases, Novi Sad, Serbia; 7School of Medicine, University of Novi Sad, Novi Sad, Serbia
Introduction: Some physiological changes in HbA1c during pregnancy should be considered to determine its optimal value for glycemic control. Erythrocytes half-life decreases during pregnancy, which is reflected in a decrease in HbA1c.
Aim: The aim of this study is to analyse HbA1c during pregnancy in healthy population of pregnant woman. Matherial and methods: The study included 77 pregnant women in the first trimester registered in Center for endocrinology UCC Kragujevac that were tested using OGTT, according to ADA criteria: pregestational and gestational diabetic women were excluded, and also determinaning thyroid parameters (fT4, TSH, TPOAb). We analyzed the HbA1c values of 46 healthy pregnant women (without gestational diabetes mellitus and thyroid disorders including autoimmune thyroiditis). The characteristics of the participants were expressed as mean ± standard deviation.
Results: The mean age of 46 healthy pregnant women was 29.4±4.5 years It has been shown that the normal range of HbA1c was 4.97-5.14% in early pregnancy, and 5.09-5.34% in late pregnancy (Table).
Conclusion: This study demonstrates that the reference range of HbA1C in healthy pregnant women during pregnancy was 4.97% to 5.34% in our population.
| HbA1c (%) | 1.trimester | 2. trimester | 3. trimester | After delivery |
| X±SD | 5.05±0.28 | 5.03±0.37 | 5.08±0.13 | 5.22±0.43 |
| (95%CI) | (4.97-5.14) | (4.92-5.14) | (4.98-5.17) | (5.09-5.34) |
| glycemia during OGTT(mmol/l) (min-max) | 1.trimester | 2. trimester | 3. trimester | After delivery |
| 0. min | 4.0-4.78 | 3.6-4.56 | 3.43-4.37 | 4.15-4.95 |
| 60. min | 4.3-7.26 | 4.95-7.99 | 5.77-8.43 | |
| 120. min | 4.04-6.12 | 4.23-6.59 | 5.27-7.49 | 4.16-6.16 |
Keywords: HbA1c, OGTT, pregnancy
Article tools
My recent searches
My recently viewed abstracts
Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
© Bioscientifica 2024 |
Privacy policy |
Cookie settings
BiosciAbstracts
Bioscientifica Abstracts is the gateway to a series of products that provide a permanent, citable record of abstracts for biomedical and life science conferences.
Find out more