Endocrine Abstracts

Aim: Study results of ultrasound dopplerography of the heart in patients with neuroischemic form of diabetic foot syndrome associated with chronic heart failure.

Material and methods: We examined 64 patients with DM 2 and DFS in the neuroischemic form on the basis of the Department of Surgery of the AndesMI. The patients were divided into 4 groups:1 gr – patients with neuroischemic form of DFS and CHF– 15 patients, gr. 2 – patients with neuroischemic form of DFS without CHF – 18 patients, Gr. 3 – patients with neuroischemic form of DFS, CHF and dyscirculatory encephalopathy stage 2–3 – 16 patients, gr. 4 – persons with CHF without D 2 15 patients. All patients were subjected togeneral clinical, biochemical, hormonal (IRI, C-peptide, inflammation marker-pro-inflammatory cytokine TNF-a, vascular endothelial growth factor (VEGF-A), and instrumental research methods – Doppler ultrasound of the vessels of the brain, lower extremities, ECG, Echo-ECG, bacteriological analysis of discharge from the wound, as well as statistical methods.

Results: There is a significant difference in the indicators of central hemodynamics in the studied groups compared with the norm: for example, LV EDR, ESV, EDV, LV EFR (P<0.05), data on the average pressure in the pulmonary artery, the time of slowing the blood flow of early diastolic filling, TZSLV (P< 0.001);Thus, in patients of the studied groups, significant deviations of the Echo-ECG, which requires further study.

Conlusion: 1. Among the risk factors, hereditary burden for DM dominated – only 21 cases out of 60 (35%), smoking – only 49 cases (81.6%), alcoholism