Searchable abstracts of presentations at key conferences in endocrinology
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Society for Endocrinology Endocrine Update 2023

Society for Endocrinology Clinical Update 2023

Workshop G: Disorders of appetite and weight

ea0091wg1 | Workshop G: Disorders of appetite and weight | SFEEU2023

Severe insulin resistance

Al-Riyahi Mohammad

A 46-year-old lady with background of type 2 DM with severe insulin resistance, hemochromatosis, bipolar disorder, glaucoma, diabetic neuropathy, hypertension, GERD, necrobiosis lipoidica, PCOS and hypercholesterolemia is followed up in complex type 2 diabetes clinic for severe insulin resistance. Her BMI is 25.7, she has freestyle libre with blood glucose readings around 15mmol/l85% of the time. HbA1c 111 on June 2022, she is on humalog 265units 7 times/day and 285units at be...

ea0091wg2 | Workshop G: Disorders of appetite and weight | SFEEU2023

Severe hyperandrogenism due to ovarian hyperthecosis in a young woman

Ahamed Sadiq Shafana , Jeyaka Neha , Maltese Giuseppe , Johri Nikhil , Joshi Mamta , Hyer Steve

Case History: Hyperandrogenism is a relatively common clinical problem. However, severe hyperandrogenism causing virilisation is rare. A 22-year-old lady with no significant past medical history, presented with oligomenorrhoea, hirsutism and male pattern hair loss over last 3 years duration. She has no acne or change in voice or clitoromegaly. She was also noted to be having high BP on clinic visit and grade 1 acanthosis nigricans.Investigations: Her tot...

ea0091wg3 | Workshop G: Disorders of appetite and weight | SFEEU2023

Clinical utility of GnRH analogues in female androgen excess due to severe insulin resistance

Cussen Leanne , McDonnell Tara , Miller Clare , Madden Doyle Lauren , W O'Reilly Michael

Lipodystrophy represents a broad spectrum of disorders, subdivided depending on aetiology (congenital or acquired) or the extent of adipose tissue absence (generalised or partial). A lack of adipose tissue results in systemic insulin resistance and ectopic fat deposition, which predisposes patients to metabolic syndrome and associated conditions such as non-alcoholic fatty liver disease and diabetes mellitus. Additionally, severe hyperinsulinaemia can generate ovarian androgen...

ea0091wg4 | Workshop G: Disorders of appetite and weight | SFEEU2023

Extreme hyperandrogenism secondary to PCOS with weight gain

Bashir Kefah , Tarigopula Giridhar , Mitchell Catherine , Al-Ansari Mustafa , Ling Yong , Minhas Raisa

A 45-year-old female presented with secondary amenorrhea. Since menarche, her period has been irregular, which she initially managed with oral pills, which were discontinued in 2009. Subsequently, she does have complete secondary amenorrhoea. She has hirsutism at the age of 20. Which was initially well controlled with oral contraceptive pills but has been getting worse over the years. Ferriman-Gallwey’s score was high. She also stated that her weight had been steadily inc...

ea0091wg5 | Workshop G: Disorders of appetite and weight | SFEEU2023

A Case of non-diabetes hypoglycaemia: A dual diagnostic challenge

Zia Rao Komal , Tharma Jasmine , Haboosh Sara , Sen Gupta Piya , Carroll Paul , Saqib Aaisha

A 47-year-old female presented to the Emergency department following an episode of loss of consciousness at home that her daughter had identified as due to hypoglycaemia (using her husband’s capillary blood glucose meter 1.1mmol/l) and treated. She reported several episodes of fainting, sweating and generalised weakness over 6 months which improved after eating snacks. There was no previous history of diabetes; she had been diagnosed with Graves’ disease 6 months pre...

ea0091wg6 | Workshop G: Disorders of appetite and weight | SFEEU2023

Post-prandial hypoglycaemia of unknown origin

Koutroukas Vaios , Dhatariya Ketan , Brooke Antonia

Introduction: α 19-year-old female patient with no past medical history presented with multiple collapses following exercise due to hypoglycaemia. From the history it transpired that she had had previous symptoms consistent with hypoglycaemia on multiple occasions, with no relation to fasting or food or a specific diurnal or nocturnal pattern. The two most severe episodes (requiring paramedic treatment) were in the recovery period from anaerobic exercise. Her body mass in...