Searchable abstracts of presentations at key conferences in endocrinology
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Society for Endocrinology Endocrine Update 2023

ea0091p1 | Poster Presentations | SFEEU2023

Hereditary Paraganglioma-Phaeochromocytoma Syndrome: A case of malignant paraganglioma discovered following surgery for breast carcinoma

Khan Shaila , Bahowairath Fatima , Palazzo Fausto , Todd Jeannie

Section 1: Case: A 42-year-old woman developed central chest pain four hours after undergoing right mastectomy for intraductal breast carcinoma. Serial blood pressures were recorded as significantly elevated, up to 240/130mmHg. There was no history of new-onset headaches, palpitations, anxiety, hirsutism, change in weight or easy bruising. She had no other significant past medical history or family history. Section 2: Investigations : An electrocardiogra...

ea0091p2 | Poster Presentations | SFEEU2023

Is it MEN2B or not? That is The Question

Subramaniam Yuvanaa , Lee Jessica , de Benito-Llopis Laura , Sharma Aditi

A 35-year-old gentleman was referred to our Endocrinology department by Moorfields Eye hospital. He reported a one-year history of visual decline in his right eye, which led to prescription glasses, and incidental finding of bilateral conjunctival nodules. He had reduced visual acuity (pinhole right eye: 6/24 and left eye 6/6) and prominent corneal nerves on slit-lamp examination. He underwent an excisional biopsy of the conjunctival nodules confirming bilateral conjunctival n...

ea0091p3 | Poster Presentations | SFEEU2023

A rare case of hypergonadotropic hypogonadism: A combination of two rare entities

Ssemmondo Emmanuel , Sathyapalan Thozhukat , Aye Mo , Mongolu Shiva , Deshmukh Harshal

Case History: This 19-year-old Caucasian female was seen in the Endocrine clinic with history of primary amenorrhea. She had a low sexual drive, no breast development but reported presence of axillary and pubic hair growth. Her main concern was whether she would be able to conceive. She had no comorbidities and took no regular medications. She never smoked and consumed no alcohol. On examination, she was 171 cm tall with a weight of 65.5 kg. She had normal external female geni...

ea0091p4 | Poster Presentations | SFEEU2023

A case of acute intermittent porphyria in a pregnant lady with hyponatraemia

Haq Rizwan , Murray Emma , Hamilton Paul , Wallace Helen , Mullan Karen

Case History: A 27 year-old lady, seven weeks gestation presented to ED during her second pregnancy with abdominal pain, vomiting, constipation and hyponatraemia (Na = 114mmol/l). She had attended twice earlier during her pregnancy with presumed hyperemesis gravidarum. Because urinary sodium was elevated at 181mmol/l, dehydration was deemed unlikely and she was initially treated as SIADH with 1.2L fluid restriction and 2.7% 200mls of hypertonic saline. Sertraline was held. Rep...

ea0091p5 | Poster Presentations | SFEEU2023

An unusual case of adrenal mass

Noel Lauran , Cavlan Dominic , Randall David

Case history: A 59 year old woman presented to hospital with severe abdominal pain, diarrhoea and vomiting. Her past medical history included end stage renal failure of unknown cause, renal transplant with antithymocyte globulin (ATG) induction ten years prior, treated pulmonary tuberculosis, hypertension and new onset diabetes after transplant (NODAT).Investigations: A CT scan of the abdomen demonstrated an 85 x 74 x 96mm heterogenous mass arising from ...

ea0091p6 | Poster Presentations | SFEEU2023

Hypercalcaemia in a patient with sarcoidosis and a positive functional parathyroid scan

Guma Muna , Mamoojee Yaasir , Quinton Richard , Napier Catherine , Forrest Ian

Introduction: Hypercalcaemia diagnosed in hospital setting is most commonly PTH-independent and malignancy related, whilst hypercalcaemia discovered in community setting is commonly secondary to Primary Hyperparathyroidism (PHPT). Other rare causes include granulomatous diseases such as sarcoidosis and familial hypocalciuric hypercalcaemia (FHH).Case Summary: A 73-year-old male with a background of hypertension and chronic kidney disease stage 3 was foun...

ea0091p7 | Poster Presentations | SFEEU2023

Calciphylaxis in a patient with hypoparathyroidism complicated by hypercalcaemia secondary to immobility

van Heeswijk Isabelle , Havill Lynsey , Kinton Rebecca , Ugur Antonia , Hughes David

Section 1: Case history : The case concerns a 53-year-old gentleman who developed calciphylaxis following a bioprosthetic aortic valve replacement. His past medical history included Multiple Endocrine Neoplasia Type 1 (MEN-1) for which he had previously undergone total parathyroidectomy with failed graft auto-transplantation. The resulting hypoparathyroidism was managed with alfacalcidol and calcium supplements. Post cardiac valve replacement he developed acute renal injury an...

ea0091p8 | Poster Presentations | SFEEU2023

A rare case of FGF23 producing tumour

Munisamy Narmadha , Azman Nur , Lambert Kimberley

Case history: A 67-year-old lady was referred to endocrinology with an 8-year history of mild hyperparathyroidism with Parathyroid hormone of 7.4 -15.3 pmol/l (Normal -1.95-8.49). Her corrected calcium ranged from 2.46-2.66 mmol/l (Normal 2.2 -2.62), phosphate 0.63 -1.0 mmol/l (normal 0.8-1.5), normal renal function and normal vitamin D. Her urine calcium to creatinine ratio was 0.7 mmol/mmol (Normal 0-0.4).Investigations and treatment: She had myalgia d...

ea0091p9 | Poster Presentations | SFEEU2023

Spontaneous haemorrhage into parathyroid adenoma masquerading as parathyroid carcinoma

North Matthew , Bhatt Yogesh , Cohen Mark

Case history: A 63-year-old female was admitted to our hospital in January 2022 with neck swelling that had developed over five days with associated dysphagia to fluids. Biochemistry revealed severe hypercalcaemia with a corrected calcium of 3.82 mmol/l (2.20 - 2.60 mmol/l) and PTH of 78.7 pmol/l (1.6 - 6.9 pmol/l), and an associated AKI (creatinine of 174 umol/L from a baseline of 80). Ultrasound initially showed a left-sided 3 x 2 cm nodule suggestive of a large parathyroid ...

ea0091p10 | Poster Presentations | SFEEU2023

A case of hypothalamic lipoma causing Hyperprolactinemia in a patient with a family history of Birt-Hogg-Dubé syndrome

Thota Geethika , Branis Natalia

Case Presentation: A 41year old female with a medical history significant for depression presented to the clinic for evaluation of bilateral nipple discharge for 5 months. The patient reported that for the last 5 months she started noticing expressible nipple discharge. She reported no associated headaches, vision changes. She denies the use of vitamins, supplements, herbal remedies. No associated fatigue, changes in the shoe/ring size, heat/cold intolerance, tremors, recent w...

ea0091p11 | Poster Presentations | SFEEU2023

Abstract Withdrawn...

ea0091p12 | Poster Presentations | SFEEU2023

A rare case of Hyperparathyroidism Jaw Tumour Syndrome without jaw tumours

Mulholland Sarah , Lewis Alex

Case History: A 19-year-old female presented with painful left shoulder after slipping whilst doing press-ups. Plain x-ray showed a proximal humeral fracture, as well as a large bone cyst raising concerns of a pathological fracture. She had no past medical history and was not taking any regular medications. On further questioning she did complain of a 2 year history of bilateral painful shoulders and left knee pain. Family history was significant for her father suffering prima...

ea0091p13 | Poster Presentations | SFEEU2023

Phaeochromocytoma in pregnancy: not all hypertension is essential

Mankumare Mohitraje , Kejem Helmine , Myers Jenny , Mumby Clare

Case history: We report a case of a 36-year-old female. She was Para 1 and 10 years prior had a vaginal delivery of a normal sized infant after an uncomplicated pregnancy. She was subsequently diagnosed with hypertension managed with Ramipril-10mg. She booked in her second pregnancy at 12 weeks/gestation. Ramipril had been stopped at positive pregnancy test and booking blood pressure was 139/85. Labetalol was commenced and she was seen in the pregnancy hypertension clinic....

ea0091p14 | Poster Presentations | SFEEU2023

Hypercalcaemia and delusions of blood poisoning: a parathyroid adenoma refractory to ultrasound-guided ethanol ablation

Conti Alessandro , Anderson John , Goodchild Emily

Case history: An 85-year-old man with primary hyperparathyroidism, resistant to cinacalcet, presented to hospital with paranoid delusions, weakness, constipation and thirst. His past medical history was of vitamin D deficiency and arthritis of the spine. Regular medications were lansoprazole, senna, and fluticasone nasal spray. He was a never-smoker and had no relevant family history. Neck examination was unremarkable.Investigations: Corrected serum calc...

ea0091p15 | Poster Presentations | SFEEU2023

What is the role of 11C Methionine PET-CT in the clinical evaluation of ACTH-dependent Cushing’s disease?

Idowu Adetokunbo , Hla Mon , Qureshi Sheharyar

Case History: 26 year old man with uncontrolled hypertension and weight gain over the last 10 – 15 years associated with abdominal stretch marks. His past medical history includes hypertension managed with four oral anti-hypertensive agents and a BMI of 36.74 kgm2 (with centripetal obesity). There is no family history of hypertension.Investigations: However, there was historical biochemical evidence of hypokalaemia (between 2.6 – 3.2mmol/l) in ...

ea0091p16 | Poster Presentations | SFEEU2023

Oncocytic parathyroid adenoma presenting with refractory hypercalcaemia and multiple incidental Brown tumours

Azman Nur , Munisamy Narmadha , Le Carpentier Dana , Syed Maria , Spraggs Paul , Li Voon Chong Jimmy , Lambert Kimberley , Parsad Meenakshi

Case History: A 61-year-old Caucasian female from Ukraine presented with severe hypercalcaemia following routine blood tests performed by the GP. She reported symptoms of back pain and joint pains. She had renal stones 10 years prior. No history of thiazide or lithium use. No red flags; no change in appetite or weight loss. There was no familial history of Multiple Endocrine Neoplasia (MEN). Examination of her neck, cardiorespiratory, abdomen and breasts were normal. <p cl...

ea0091p17 | Poster Presentations | SFEEU2023

47 XYY Syndrome; compared to XXY; do both ‘Y’ and Thyroxine differ?

Solomon Andrew , Haddad Aiman , Saifee Tabish

Case history: We present a 61-year-old male with a background history of 47 XYY syndrome who was referred to the endocrine outpatient service with abnormal thyroid function tests. He has mild learning disabilities, asthma, action tremor, erectile dysfunction, and type 2 diabetes. He was tall in stature with obvious clinodactyly. He had been evaluated for his tremor by our Neurology colleagues. Investigations: His blood tests results were as follow- TSH 5...

ea0091p18 | Poster Presentations | SFEEU2023

Recurrent symptomatic pituitary hyperplasia mimicking macroprolactinoma in pregnancy

Onyema Michael , Tanveer Quratulain , Khalilova Samira , Lajeunesse-Trempe Fannie , Aylwin Simon , Dimitriadis Georgios K.

(1) 30-year-old woman presenting at 34 weeks of pregnancy with symptoms of persisting headaches, diplopia and nausea. She presented again 4 years later with similar symptoms in a subsequent pregnancy at 35 weeks with additional complaints of blurred peripheral vision. (2) During her first pregnancy biochemistry revealed marked prolactin elevation (14,000 mIU/l). A non-contrast MRI scan of the pituitary revealed significant enlargement of the gland (22 x 14.4 x 12.5mm) bey...

ea0091p19 | Poster Presentations | SFEEU2023

Heart failure as the index presentation of Addison’s disease: Case Report

Joseph Siphy

Background: Cardiac failure is an infrequently reported complication of Addison’s disease which is unique in its reversibility. We report a rare case of heart failure as the initial presentation of Addison’s disease.Case Summary: A 39-year-old gentleman presented with classical features of heart failure and hypotension. His Echocardiogram showed moderately impaired left ventricular function. Addison’s disease was suspected due to hyponatre...

ea0091p20 | Poster Presentations | SFEEU2023

A Preventable Gonadectomy!

Madhurya Kethireddi Keerthi , Namiq Parez , Crown Anna

A 36-year-old man from Romania was referred to the urology clinic with a two-year history of a painful left testicular swelling. On examination, both testes had multiple solid non-tender masses. An ultrasound scan of the testes showed bilateral, symmetrical infiltration of both testes, with scattered calcifications and enhanced blood flow. The differential diagnosis included testicular cancer, granulomatous diseases, leukaemia and adrenal rests. A CT scan showed no metastatic/...

ea0091p21 | Poster Presentations | SFEEU2023

Crystal Healing in endocrine disease

Lacey Hester , Chakera Ali , Crown Anna

We present two cases of alternative approaches to treating endocrine disease. Case 1: A 55-year-old man became steroid dependent in 2017, following a skiing accident and C3/4 fracture, for which he received 13-months of high-dose hydrocortisone. Upon cessation, he developed adrenal crisis, confirmed on short synacthen test. Hydrocortisone replacement therapy was begun. His dose was doubled, then tripled to control his symptoms, in addition to frequent re...

ea0091p22 | Poster Presentations | SFEEU2023

Cystic Prolactinoma unmasking Meningoencephalocele: When medical treatment leads to surgery

Greenhalgh Sophie , Lewis Alexander

Case history: 21-year-old male presented in November 2006 with visual loss, headaches and fatigue. No previous past medical history. Visual field testing confirmed a left temporal hemianopia with right temporal upper quadrantanopia.Investigations: Brain imaging revealed a large macroadenoma with suprasellar and lateral extension. Hormone testing demonstrated abnormalities in TSH 5.13 mU/L, Free T4 7.1 pmol/l, random Cortisol 64nmol/l and Testosterone 2.3...

ea0091p23 | Poster Presentations | SFEEU2023

A case of persistent hypercalcaemia in the treatment of granulomatous disease

Osman Nadia , Patel Henna , Gunganah Kirun

Section 1: Case history : A 49 year old South Asian gentleman was admitted to the emergency department after monitoring blood tests showed hypercalcaemia (corrected calcium of 3.67mmol/l) and acute kidney injury. He had a recent admission with a new diagnosis of miliary tuberculosis and superadded bacterial infection, complicated by a long and complex ITU admission after initiation of treatment. He was discharged home on colecalciferol 4000 units daily in addition to his anti-...

ea0091p24 | Poster Presentations | SFEEU2023

A case report: Cholestatic hepatitis secondary to carbimazole therapy in the management of Graves’ thyrotoxicosis

Lei Yee Shar , Abouglila Kamal

Section 1: Case history: A 51-year-old lady was referred to our endocrinology clinic with a 6-month history of palpitations, generalized muscle aches, heat intolerance, increased sweating and significant unintentional weight loss. She is normally fit and well without any significant past medical problem. Her thyroid function tests showed thyrotoxicosis picture with TSH < 0.05 miu/L, Free T4 76pmol/l, Free T3 > 30.8 pmol/l with positive TSH receptor antibodies ( 34.9U/L...

ea0091p25 | Poster Presentations | SFEEU2023

Treat the patient not the disease - A case of a Neuroendocrine Tumor presenting as Cushing’s

Sharma Bhavna , Qureshi Asjid , Di Marco Aimee , Partridge Sarah , Wernig Florian

68 years old male was admitted with cough and fever during the second UK covid surge. Recent new diagnosis of hypertension and diabetes with worsening psychotic symptoms on background of schizophrenia. Noted previous hypernatremia, hypocalcemia, hypomagnesemia along with marked refractory hypokalemia and metabolic alkalosis. Cushing’s syndrome phenotype was not noted. Failed to suppress cortisol during an overnight dexamethasone suppression test with plasma cortisol remai...

ea0091p26 | Poster Presentations | SFEEU2023

Non-islet cell tumour hypoglycaemia (NICTH)

Yin Yin , Srikugan lanitha , Mohandas Cynthia , Ogunko Arthur , Abedo Itopa

An 87-year-old lady was admitted to hospital with severe unexplained hypoglycaemia with capillary glucose of 1.8 mmol/l and went on develop recurrent episodes of symptomatic hypoglycaemia during this admission. She had a background history of diabetes mellitus, well under controlled with diet and a previous diagnosis of solitary fibrous pleural tumour of left lung, which was resected completely in 2013 but reoccurred in 2022 with left sided pleural effusion. Her liver and rena...

ea0091p27 | Poster Presentations | SFEEU2023

How we treated a challenging case of Radioiodine (RAI)-refractory Papillary Thyroid Carcinoma in a young woman!

Thota Geethika , Roy Roopa

Case Information: A 39-year-old woman from Guatemala with no significant past medical history initially presented with swelling in neck & obstructive symptoms. She was diagnosed with papillary thyroid carcinoma in March 2017 & underwent a total thyroidectomy& LN Dissection. Pathology showed multifocal, largest tumor size 3.2 cm, with one involved lymph node, significant angiolymphatic invasion, and was stand was staged as initially received 121 mCi of radioactive i...

ea0091p28 | Poster Presentations | SFEEU2023

Mitochondrial DNA Depletion syndrome 1 (MNGIE type) – a rare cause of premature ovarian failure?

Matheou Michael , Tan Garry D , Karpe Fredrik , Brady Stefen , Kent Louisa , Javaid Kassim , Marshall Jonathan , Shears Deborah , Turner Helen E

Case history: A 39 year old lady was being investigated and managed for premature ovarian insufficiency (onset aged 29y) associated with an unusual constellation of symptoms. Following normal childhood and pubertal development, she subsequently developed fatigue, multiple gastrointestinal symptoms and was underweight with evidence of weight loss, and a most recent BMI of 17 kg/m2. She had previously been reviewed due to marked absence of subcutaneous fat in the lowe...

ea0091p29 | Poster Presentations | SFEEU2023

Pathological fracture in Osteitis Fibrosa Cystica: a late skeletal complication of uncontrolled primary hyperparathyroidism

Vellacott Georgia , Htet Zaw , McLaren Andrew , Ballav Chitrabhanu

Case history: An 80-year-old woman, with a background of primary hyperparathyroidism (PHPT), presented to the emergency department with a spontaneous pathological fracture of her left femoral shaft. Blood tests revealed severe hypercalcaemia (corrected calcium 3.26 mmol/l, 2.1 – 2.55) after being lost to follow up for twenty years. She was vitamin D replete after supplementation, had normal renal functions (creatinine 76 umol/L, 50-98), and high parathyroid hormone (PTH 1...

ea0091p30 | Poster Presentations | SFEEU2023

Sleep - associated seizures in a thyrotoxic patient

Vivienne Obi Ngozi , Mendis Budd

History: A 33-year-old man presented to emergency with weight loss of 3 months duration, intermittent sweating and heat intolerance. He had a brother with thyroid disease treated with levothyroxine and did not smoke. He was tremulous and short of breath, with a regular heart rate of 115b/min and blood pressure of 143/71mmHg. Initial assessment showed mildly diffuse non-tender goitre with a bruit, no cervical lymphadenopathy, mild proptosis with mild scleral congestion. TSH 0.0...

ea0091p31 | Poster Presentations | SFEEU2023

A Case of Ipilimumab induced New-Onset Type1 Diabetes Mellitus in a Patient with Renal Cell Carcinoma

Thota Geethika , Luo Hongxiu

Case Presentation: A 50-year-old female with a recent diagnosis of Renal cell cancer (RCC) with hepatic metastasis and hypothyroidism was referred to the clinic for the management of Diabetes Mellitus (DM). The patient was diagnosed with RCC in 2017 and was treated with immunotherapy Ipilimumab for two years. No family history of Diabetes Mellitus and denies history of corticosteroid usage. No previous episodes of Diabetic Ketoacidosis. She was diagnosed with Diabetes Mellitus...

ea0091p32 | Poster Presentations | SFEEU2023

Non-islet cell tumour hypoglycaemia (NICTH) caused by an intrathoracic tumour and responding well to glucocorticoid therapy

Ahamed Sadiq Shafana , Jeyakar Neha , Maltese Giuseppe , Johri Nikhil , Joshi Mamta , Hyer Steve

Case History: An 81-year-old gentleman was brought to A&E by ambulance after being found to be hypoglycaemic at home by paramedics. His wife reported that he experienced unsteadiness and slurred speech after waking up in the morning and she called the emergency number. On arrival of paramedics, his capillary blood glucose was found to be 1.2 mmol/l and he was administered intravenous dextrose. He also had a couple of similar episodes which were resolved with food. He is no...

ea0091p33 | Poster Presentations | SFEEU2023

Aarskog Syndrome - A rare cause of primary hypogonadism

Chaudhary Aparna , Narayanan Ram Prakash

Case history: We present a case of a 34-year-old male diagnosed with bilateral gynecomastia referred to the endocrine clinic. Notable background of left cryptorchidism with orchidopexy at the age of 15, delayed puberty, chronic testicular pain and atopic dermatitis. On examination he had short stature, hypertelorism, low set ears, broad short hands, brachydactyly and clinodactyly of 5th fingers. There was no evidence of cleft lip/palate, teeth abnormalities or inguinal/abdomin...

ea0091p34 | Poster Presentations | SFEEU2023

Fertility options for a rare cause of primary amenorrhea

Chirila-Berbentea Veronica , Bhattacharya Beas

Section 1: Case history: A 17 year old lady who was referred to our endocrinology clinic due to primary amenorrhoea in 2019. She had well-established secondary sexual characteristics and hyperprolactinaemia. Patient mentioned one episode of PV bleed when she was about 10 years old. Section 2: Investigations: Bloods (Feb2020) showed: FSH: 6.2 IU/l; LH: 5.1IU/l; prolactin 1.048 mIU/l; testosterone 1.3 nmol/l. MRI pituitary: lipoma of corpus calosum and pit...

ea0091p35 | Poster Presentations | SFEEU2023

Severe hyperprolactinaemia associated with domperidone with normal MRI pituitary

Thackray Kerrie , Kaplan Felicity

Section 1: Case History: A 28 year old female initially presented to Endocrinology in 2020 with hirsutism and irregular menstruation but reassuring biochemistry. In 2022, she was referred to Gastroenterology with weight loss, vomiting and dyspepsia and found to have severe hyperprolactinaemia. Past medical history included anxiety/depression. Current medication was esomeprazole 40mg OD and mebeverine 135mg TDS. Cyclizine 50mg TDS had previously been prescribed, followed by dom...

ea0091p36 | Poster Presentations | SFEEU2023

An unusual presentation of Grave’s disease

Younes Younes R , Thomas Kerushan , Lakshmipathy Kavitha , Nayyar Vidhu , Zachariah Sunil , Clark James , C T Field Benjamin , Emmanuel Julian

We present a case of a 44-year-old female with fluctuating thyroid function over 12-14 years. The patient originally presented with a high TSH, normal free T3/T4 and a negative anti-TPO antibody. She was initially monitored, then went onto Levothyroxine replacement in an antenatal setting. Subsequently, 12-18 months later, she presented with hyperthyroid symptoms and vastly elevated TSH-receptor-antibody (TSHR-ab) titre of >10 IU/L, the upper limit of normal being 2.9 IU/L...

ea0091p37 | Poster Presentations | SFEEU2023

Craniopharyngioma: A Comprehensive Overview of a Challenging Pituitary Mass

Mcgown Patrick , Narula Kavita , Nair Ramesh , Gontsarova Anastasia , Jaunmuktane Zane , Ferguson Mark , Mendoza Nigel , Martin Niamh , Meeran Karim , Mehta Sanjeev

Case history : A 44-year-old female presented with 6-week history of gradual deterioration in her left vision associated with eye pain. She saw an ophthalmologist who noted that she had reduced visual acuity (6/24) and colour vision (Ishihara colour vision score 3/15) in her left eye with left relative afferent pupillary defect (RAPD). It was thought that she may have a left retrobulbar neuritis so she was advised to attend A&E for an urgent neurology assessment. On examin...

ea0091p38 | Poster Presentations | SFEEU2023

Beneficial side effects: A case of difficult hyperthyroidism treated with Lithium

Acosta Allan , Hameed Ali

A case of a 48-year-old lady who is under follow-up in the clinic at Causeway Hospital, Northern Ireland for hyperthyroidism. She has a medical history of SLE under follow-up Rheumatologists and bronchial asthma. She presented with palpitations, tremors, sweating, and heat intolerance. On examination, the patient appears anxious. Blood pressure was 130/80, PR 140, RR 20, T 37, SPO2 98% A. Her eye examination revealed no lid lag, exophthalmos, and no redness. Examination of the...

ea0091p39 | Poster Presentations | SFEEU2023

An unusual case of neuropathy

Chirila-Berbentea Veronica , Bhattacharya Beas

Case history: This 28 year old lady with a new diagnosis of T1DM (April 22) and uveitis complained of severe pain over the trunk described as a burning sensation but not associated with any neurological deficit. There is no history of head trauma, neck trauma or radiation to head and neck area and no skin changes or spinal deformity. She has developed this pain after starting insulin in April 22. Investigations: May 22: Hb 119, MCV: 85.0; U&Es:normal...

ea0091p40 | Poster Presentations | SFEEU2023

Rare Case of Metastatic Glucagonoma, A Diagnostic Twist

Amjad Wajiha , Randall Joanne

73 year old lady with metastatic pancreatic cancer referred to diabetes clinic with worsening of her diabetes control. She was primarily under care of Gastroenterology department, for her symptoms of weight loss, abdominal pain, diarrhoea, sweating and anaemia. Her scan showed metastatic pancreatic cancer arising from tail of pancreatic with metastasis to liver. The liver biopsy of secondary liver deposit was not conclusive. She had borderline diabetes at her presentation wors...

ea0091p41 | Poster Presentations | SFEEU2023

Cushing’s Disease in the time of COVID

Tyndall Victoria , Ritchie Stuart

Case history: A 37 year old mother of two was referred to DGH by the GP for possible PCOS in 2019. She had an 18 months of weight gain, hirsuitism, oligomenorrhoea, abdominal distension, back pain and fatigue. Medical history included asthma and she worked as a teacher. On Endocrine clinic review, she was noted to be floridly Cushingoid. Urgent referral to tertiary Endocrinology in Edinburgh was auctioned and a diagnosis of Cushing’s Disease was made alongside multiple re...

ea0091p42 | Poster Presentations | SFEEU2023

A treasure hunt! An unusual presentation of benign thyroid tissue as neck masses

Thota Geethika

Case Description: A 66-year-old lady with a past surgical history of partial left lobectomy for unclear reasons 30 years ago was referred by the surgeon for evaluation of thyroid nodules. She reported noticing palpable neck masses but didn’t report associated heat/cold intolerance, palpitations, diarrhea, tremor, fatigue, skin/hair /sleep /weight/appetite changes. No associated neck pain, dysphagia, fever, upper respiratory tract infection symptoms, or vaccination. No obs...

ea0091p43 | Poster Presentations | SFEEU2023

Corticosteroids can prolong the duration of COVID-19 shedding, in the absence of symptoms

Thomas Kerushan , R Younes Younes , Lakshmipathy Kavitha , Nayyar Vidhu , Zachariah Sunil , Clark James , C T Field Benjamin , Emmanuel Julian

A recent case series commented on adverse COVID-19 outcomes among patients with Cushing’s syndrome, despite minimal symptoms and low inflammatory markers. Excessive glucocorticoids can impede adaptive immune response to viruses, leading to increased infection risks (1). Sarker et al discussed glucocorticoids binding to viral spike-proteins, inhibiting receptor interactions and contributing to prolonged positive swabs, in the absence of symptoms (2). We report the c...

ea0091p44 | Poster Presentations | SFEEU2023

Challenges in the management of chronic hypoparathyroidism and severe hypocalcaemia in post thyroidectomy- is there a rationale in using recombinant human parathyroid hormone?

Nijith Lakshmi , Chan Sigmond , Ward Lisa , Bottoms Nicole , Banerjee Ritwik

39-year-old female, with a past medical history of Graves Hyperthyroidism, underwent total thyroidectomy 18 years ago, with resultant hypoparathyroidism, hypocalcaemia and hypothyroidism. Her calcium levels are usually in the range of 1.6-1.8 mmol/l, but there are times when it can go to dangerously low levels (range of 1.4-1.15 mmol/l) causing symptoms, sometimes with ECG changes, requiring hospital admissions and IV calcium replacements. There is no parathyroid activity dete...

ea0091p45 | Poster Presentations | SFEEU2023

A case of hypogonadotropic hypogonadism (HH) due to CHARGE syndrome

Shazra Mariyam , Elkhateeb Nour , Park Soo-Mi , Parkinson Craig

Case history: A 26-year-old man was referred to the Endocrine Clinic due to lack of erections and infrequent shaving for 12 months. An extensive past medical history was noted, the majority of which was attributed to a diagnosis of cerebral palsy. Problems included feeding difficulties from birth with NG, followed by PEG feeding from age 3 to 20, gross motor, speech and language developmental delay, bilateral severe hearing impairment necessitating hearing aids, long sightedne...

ea0091p46 | Poster Presentations | SFEEU2023

An unusual presentation of Pituitary macroadenoma in an acute medical take

Yin Yin , Tan Jessica , Srikugan lanitha , Abedo Itopa , Ogunko Arthur , Mohandas Cynthia

Case History: A 64-year-old gentleman presented to the emergency department with acute onset dizziness, nausea, vomiting and difficulty in standing. Although his symptoms lasted only for a few hours, his neurological examination was unremarkable. His past medical history included atrial fibrillation, factor V Leiden deficiency and previous left lower limb DVT. He was not on any medications that can cause hyperprolactinaemia. The stroke team who reviewed him initially diagnosed...

ea0091p47 | Poster Presentations | SFEEU2023

Pre-clinical Autoimmune Adrenalitis, biochemically diagnosed; Treat or Not?

M Gharib Ahmed Ahmed , Cheyne Elizabeth

The Case: We are presenting a 51-year-old Caucasian lady with known type 1 diabetes who was diagnosed with Autoimmune Addison’s Disease (AAD) during investigation of persistent hyponatremia. She was admitted with DKA back in November 2022 that was believed to be due to gastroenteritis. Usually, her diabetes control has been reasonable over the years with no severe chronic complications or diabetes-related hospital admissions. In the hospital, she suffered from ongoing hyp...

ea0091p48 | Poster Presentations | SFEEU2023

Poly Cystic Ovarian Syndrome: Common condition, with unusual presentation

Amjad Wajiha

18 year old female was referred to endocrinology from Paediatric and adolescent gynaecology with secondary amenorrhea. She had her menarche at age of 15 years with profuse bleeding for three days only, no spontaneous periods afterwards. She had no symptoms of weight gain, increased hair growth, galactorrhea, headache or any skin changes. She had significant history of hair loss. She had normal milestones. She achieved her adrenarche and thelarche at age of 12-13 years. Family ...