Searchable abstracts of presentations at key conferences in endocrinology
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45th Annual Meeting of the European Thyroid Association (ETA) 2023

Poster Presentations

Case Reports 2

ea0092ps3-25-01 | Case Reports 2 | ETA2023

Uncommon findings in a thyroid nodule: A case report of osseous metaplasia in a benign thyroid lesion

Sorina Martin Carmen , Nacu Miruna , Enache Oana , Parfeni Ovidiu , Zaki Naji Al Jumaili Ahmed , Enciu Octavian , Sirbu Anca , Fica Simona

Introduction: Although calcifications are a relatively common finding on a thyroid ultrasound, present in both benign and malign lesions, osseous metaplasia (OM) is a peculiar discovery, with only a few described cases in literature so far. Common pathophysiological explanations include abnormalities of bone morphogenetic protein family members and basic fibroblast growth factor. Most of the case reports are presenting OM in association with malign lesions, often with papillar...

ea0092ps3-25-02 | Case Reports 2 | ETA2023

A rare case of autoimmune polyglandular syndrome type 2

Zavrashvili Nino , Margvelashvili Natia

A Rare Case of Autoimmune Polyglandular Syndrome Type 2 Autoimmune polyglandular syndromes (APS) are a group of immune-endocrine syndromes that cause autoimmune destruction of multiple endocrine organs. The most common in this group is APS type 2, which frequently presents with primary adrenal insufficiency with autoimmune thyroid disease and/ or type 1 diabetes mellitus. We present a case of 46 year old male, with no significant medical history who presented in our clinic wit...

ea0092ps3-25-03 | Case Reports 2 | ETA2023

Report of a case with new onset of thyroid eye disease following viral vector SARS-COV-2 Vaccine

Armeni Anastasia , Markantes Georgios , Stathopoulou Alexandra , Kanakis Menelaos , Michalaki Marina

Introduction: The occurrence or worsening of thyroid eye disease (TED) after SARS-CoV-2 mRNA vaccines is extremely rare whereas has not been reported following viral vector vaccination. In the region of South-West Greece during the COVID-19 pandemic, a case of de novo appearance of TED referred to the Endocrinology Department of our hospital, following viral vector SARS-COV-2 vaccine.Case report: The patient was a 62-year-old woman, heavy smoker (40 pack...

ea0092ps3-25-04 | Case Reports 2 | ETA2023

Dupilumab-related graves disease: A case report

Gama Catarina , Oliveira Margarida , Antunes Carolina , Calvo Paula , Lopes Leonor , Cunha Clara , Marques Bernardo , Branco Pedro , Sequeira Duarte Joao

Introduction: Graves Disease (GD) is an autoimmune disease, in which CD4+ Th2 cells secrete interleucin-4 (IL-4) and IL-5 and activate antibody production. IL-4 has been considered a therapeutic target for treatment of immune-related diseases, by enhancing and redirecting T and B cell function. Dupilumab, a monoclonal antibody, inhibits IL-4 and IL-13 and is currently used for treatment of atopic dermatitis, nasal polyposis and asthma. There is a single case report of painless...

ea0092ps3-25-05 | Case Reports 2 | ETA2023

A rare case of euthyroid gravès ophthalmopathy with negative trabs titers

Margvelashvili Natia , Zavrashvili Nino

A Rare Case of Euthyroid Grave’s Ophthalmopathy with Negative TRAbs titersIntroduction: Graves’ ophthalmopathy (GO; also known as thyroid-associated ophthalmopathy or thyroid eye disease) is clinically evident in 25–50% of patients with Grave’s disease. While the majority of patients experience only mild ocular symptoms, 3–5% of patients with GO suffer from severe disease (2). The spectrum of eye manifestations ranges from lid la...

ea0092ps3-25-06 | Case Reports 2 | ETA2023

DIfferent presentations of thyroid dermopathy

Janic Tamara , Stojkovic Mirjana , Klet Sanja , Marković Bojan , Beleslin Biljana , Ciric Jasmina , Zarkovic Milos

Graves’ disease (GD) is an autoimmune disease that can affect other tissues in addition to the thyroid gland. Depending on the intensity of the immune response, in addition to hyperthyroidism, orbitopathy, dermatopathy and acropachy can also occur. Extrathyroidal manifestations of GD are most often the result of a more pronounced immune response. Thyroid dermatopathy (TD) is a rare extrathyroidal manifestation of GD, almost always associated with Graves’ orbitopathy ...

ea0092ps3-25-07 | Case Reports 2 | ETA2023

A case report of graves’ disease induced by IFN-β-1a therapy

Patrizio Armando , Viva Tommaso , Martina Ferrari Silvia , Elia Giusy , Ragusa Francesca , Rosaria Paparo Sabrina , Antonelli Alessandro , Fallahi Poupak

The risk of thyroid dysfunction induced by Interferon (IFN)-β1b therapy, in particular in patients having preexisting thyroid autoimmune disorders (AITD), is well known. We report a case of a 60-year-old female, with a 15-year history of euthyroid autoimmune thyroiditis and a 3-year history of Multiple Sclerosis (MS), in care for the evaluation of hyperthyroidism. The patient started a specific immunomodulant IFN-β1a therapy (30 μg/week) twenty months before the...

ea0092ps3-25-08 | Case Reports 2 | ETA2023

Resistance to thyroid hormone in the absence of thyroid hormone receptor mutation: A case report

Jesenko Miha , Kocjan Tomaž , Krhin Blaž , Gaberscek Simona

Introduction: Resistance to thyroid hormone beta is a genetic disease defined by impaired sensitivity of target tissue to thyroid hormone caused by mutation of thyroid hormone receptor beta gene, appearing with an incidence of 1/40,000. The characteristic biochemical profile of resistance to thyroid hormone is elevated serum thyroid hormone level and inappropriate serum level of thyrotropin (TSH) which is normal or elevated. Clinical picture is variable ranging from asymptomat...

ea0092ps3-25-09 | Case Reports 2 | ETA2023

Autoimmune hypothyroidism associated with pseudohypoparathyroidism

Shonia Natia , Zavrashvili Nino

Introduction: Hashimoto thyroiditis is an autoimmune disorder affecting the thyroid gland leading to chronic inflammation and gradual decline of the thyroid gland function eventually requiring hormone replacement. Patients present with classic symptoms and signs of hypothyroidism. The term pseudohypoparathryoidism (PHP) refers to a group of rare genetic and epigenetic disorders characterized by resistance to the action of parathyroid hormone (PTH) that activates cAMP signaling...