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45th Annual Meeting of the European Thyroid Association (ETA) 2023

Poster Presentations

Thyroid Cancer Diagnosis 2

ea0092ps2-17-01 | Thyroid Cancer Diagnosis 2 | ETA2023

The 2017 bethesda system for reporting thyroid cytopathology: the experience of a tertiary center

Markantes Georgios , Mpota Valentina , Strati Myrsini , Theodoropoulou Anastasia , Kardari Maria , Michalaki Marina

Objectives: The Bethesda System for Reporting Thyroid Cytopathology (TBSRTC) is a validated and widely used tool for thyroid nodules triage. Studies reporting on the frequency of each Bethesda category are scarce, and there are wide discrepancies in the reported results between the various centers. Our aim was to register all cytological reports of the thyroid fine needle aspiration biopsies (FNAB) reviewed in the Cytology Department of a tertiary hospital during a calendar ye...

ea0092ps2-17-02 | Thyroid Cancer Diagnosis 2 | ETA2023

Monocentric validation of the ’thyroid risk score’ (TRS) in a large series of indeterminate thyroid nodules

Muzza Marina , Colombo Carla , Vannucchi Guia , Succi Massimiliano , Palazzo Sonia , Frattini Francesco , Gentilini Davide , Gazzano Giacomo , Persani Luca , Fugazzola Laura

The diagnosis of indeterminate thyroid nodules is a challenge in cytopathology practice. To increase the diagnostic accuracy in these cases, we previously set up a ’thyroid risk score’ (TRS), derived from the sum of the scores assigned to: cytology + EU-TIRADS classification + nodule size + molecular profile. In the present study we prospectively validated the reliability of the TRS in the clinical practice. From 2018 to 2022 we evaluated 354 indeterminate nodules (2...

ea0092ps2-17-03 | Thyroid Cancer Diagnosis 2 | ETA2023

Role of cervical ultrasound in the pre-operative evaluation of central compartment lymph nodes in thyroid cancer

Retta Francesca , Mormile Albeto , Josefina Ramunni Maria , Sapino Silvia , Caracciolo Alessandra , Ravera Alberto , Canale Giovanni , Deandrea Maurilio

Background and Objective: In thyroid cancer (TC) central compartment (CC) neck dissection (CCND) should accompany thyroidectomy in case of clinical and/or cytological suspicion of lymph node (LN) metastases. Cervical ultrasound has been indicated as the first-line examination in the pre-operative staging of TC, although its diagnostic performance in evaluating CC LN is controversial. Proving that cervical ultrasound can accurately identify CC metastases would allow to use this...

ea0092ps2-17-04 | Thyroid Cancer Diagnosis 2 | ETA2023

PRO-gastrin-releasing peptide as an additional screening marker in the diagnostic work up for medullary thyroid carcinoma

Schonebaum Leonoor , van Balkum Mathe , Edward Visser W. , van den Berg Sjoerd , Peeters Robin

Background: Patients with medullary thyroid carcinoma (MTC), a neuroendocrine tumour derived from the parafollicular C-cells, often present with metastasized disease. Survival strongly correlates with stage of disease at diagnosis, illustrating the need for early diagnosis. Calcitonin (CT), a well-established tumour marker for MTC, is limited by a high rate of false positives in the screening phase. Promising new markers for MTC are procalcitonin (PCT) and progastrin releasin...

ea0092ps2-17-05 | Thyroid Cancer Diagnosis 2 | ETA2023

18F-DOPA-PET/ct in medullary thyroid cancer patients with biochemical incomplete response

Gambale Carla , Faranda Alessio , Prete Alessandro , Minaldi Elisa , Cappagli Virginia , Ambrogio Alice , Volterrani Duccio , Elisei Rossella , Matrone Antonio

Objectives: PET/CT scan with 18F-fluoro-dihydroxyphenylalanine (18F-DOPA) is an emerging useful tool in medullary thyroid cancer (MTC) patients. The question whether 18F-DOPA-PET/CT could be useful in MTC patients with biochemical incomplete response (BiR) is to clarify.Methods: Fifty-three MTC patients with BiR performed 18F-DOPA-PET/CT scan between May 2021 and December 2022 after having performed total body ...

ea0092ps2-17-06 | Thyroid Cancer Diagnosis 2 | ETA2023

Impact of lymphovascular invasion on otherwise low-risk papillary thyroid carcinomas: A retrospective and observational study

Puga Francisca , Al Ghuzlan Abir , Hartl Dana M. , Bani Mohamed-Amine , Moog Sophie , Pani Fabiana , Breuskin Ingrid , Guerlain Joanne , Faron Matthieu , Denadreis Desiree , Baudin Eric , Hadoux Julien , Lamartina Livia

Background: Presence of venous vascular invasion is a criterion of intermediate risk of recurrence in papillary thyroid carcinoma (PTC). However, the presence and type of vascular invasion (lymphatic or venous) is often underreported and its impact on PTCs without other risk features remains unknown.Objective: To evaluate the impact of both lymphatic and venous invasion on the risk of recurrence/persistence on otherwise low-risk PTCs.<p class="abstex...

ea0092ps2-17-07 | Thyroid Cancer Diagnosis 2 | ETA2023

Correlation of three thyroglobulin assays in the management of differentiated thyroid cancer (DTC) patients

Paula Biscolla Rosa , Guastapaglia Leila , Ferrer Claudia , Izabel Chiamolera Maria , Viana Lima Jr Jose , Viana Luciana , Maciel Rui , Gilberto H Vieira Jose

Correlation of three thyroglobulin assays in the management of differentiated thyroid cancer (DTC) patientsIntroduction: Thyroglobulin(Tg) is the main biochemical marker of DTC. Usual immunometric assays(IMA) are prone to interference by autoantibodies which can lead to erroneous results. LC-MS/MS has been described as an assay that may provide accurate results, however the literature reported up to 40% of undetectable rates in patients with positive thy...

ea0092ps2-17-08 | Thyroid Cancer Diagnosis 2 | ETA2023

Characteristics of incidental pappillary thyroid microcarcinomas detected by various nuclear medicine imaging techniques

Erturk Banu , Hanife Oğuz Seda , Kaya Gursan , Bozkurt Murat , Gurlek Alper

Objective: The prevalence of incidentally discovered papillary thyroid microcarcinoma (iPTMC) has increased with the expanded use of diagnostic imaging, including nuclear medicine imaging techniques. While iPTMC appears to have a better prognosis than non-incidental PTMC, it was suggested that thyroid carcinomas that were incidentally discovered during 18F-fluorodeoxyglucose positron emission tomography/computer tomography (FDG PET/CT) or parathyroid scintigraphy may have poor...

ea0092ps2-17-09 | Thyroid Cancer Diagnosis 2 | ETA2023

Clinical application of grading system in sporadic medullary thyroid carcinoma patients

Prete Alessandro , Torregrossa Liborio , Gambale Carla , Materazzi Gabriele , Elisei Rossella , Matrone Antonio

Introduction: Despite its neuroendocrine origin, only recently an international study group proposed a dedicated grading system (IMTCGS) for medullary thyroid carcinoma (MTC). IMTCGS is an independent and powerful tool able to predict disease specific survival (DSS) as well as distant metastasis-free (DMFS) and locoregional recurrence-free survivals (LRFS), regardless of other risk factors, including staging.Objectives: To evaluate the performance of IMT...