Searchable abstracts of presentations at key conferences in endocrinology
Previous issue | Volume 94 | SFEBES2023 | Next issue

Society for Endocrinology BES 2023

Glasgow, UK
13 Nov 2023 - 15 Nov 2023

Card image cap
SfE BES is the UK's leading endocrinology meeting. It will return to Glasgow in 2023.

Oral Poster Presentations

Reproductive Endocrinology

ea0094op3.1 | Reproductive Endocrinology | SFEBES2023

Are we giving enough attention to blood pressure control in turner syndrome? : Data from the international turner syndrome (I-TS) registry

Mathara Diddhenipothage Shani A.D. , Beck Katharina J. , Amiyangoda C G K , Bryce Jillian , Cima Luminita , De Groote Katya , Deyanova Yana , Globa Evgenia , Herrmann Gloria , Juul Anders , Sophie L. Kjaer Kjaer Anna , Tonnes Pedersen Anette , Poyrazoglu Sukran , Probst-Scheidegger Ursina , Sas Theo C.J. , Fica Simona , Nimali Seneviratne Sumudu , Karolina Witczak Justyna , Orchard Elizabeth , Tomlinson Jeremy W. , Faisal Ahmed S. , Turner Helen E

Introduction: Cardiovascular disease is the commonest cause of death (absolute-excess-risk:41%) in Turner Syndrome (TS). Hypertension is a major risk for circulatory-disease (up to 60%) and a key modifiable-risk factor of aortopathy, ischemic heart disease and stroke in TS. There is no current consensus for hypertension diagnosis/management in TS.Methods: Retrospective multi-centre observational study of patients aged &#...

ea0094op3.2 | Reproductive Endocrinology | SFEBES2023

Abnormal uterine bleeding (AUB) and COVID-19: investigating associations and potential mechanisms

Watters Marianne , Alvergne Alexandra , Walker Catherine , Robb Cara , Critchley Hilary , Kountourides Gabriella , Austin Argentieri , Sharp Gemma , Olszewska Zuzanna , Maybin Jacqueline

Women with COVID-19 and Long COVID (symptoms >4 weeks) have reported AUB. We investigated (i) the association between COVID-19/Long COVID and AUB and (ii) ovarian sex hormones across the menstrual cycle in women with Long COVID. Two studies were completed with ethical approvals and consent. Firstly, a retrospective online survey ‘The Covid-19 Pandemic and Women’s Reproductive Health’ was conducted March-May 2021 with UK participants >18 years old (n<...

ea0094op3.3 | Reproductive Endocrinology | SFEBES2023

Characterisation of a novel N terminally FLAG-tagged FSHR knock in mouse model to understand the physiological roles of FSHR oligomerisation

Hopkins Thomas , Johnson Gillian , Sureshkumar Sumetha , Bousfield George , Jonas Kim

The G protein-coupled receptor (GPCR), follicle stimulating hormone receptor (FSHR) plays a critical role in ovarian function and reproduction, with multiple functions in follicle growth, maturation, survival, and steroid hormone production. Yet how FSH/FSHR mediates these pleiotrophic physiological roles remains unknown. Numerous studies indicate GPCRs can regulate and diversify their actions through receptor-receptor association and the formation of dimers/oligomers. Moreove...

ea0094op3.4 | Reproductive Endocrinology | SFEBES2023

Exploring the sexual dimorphic development of human external genitalia

Lecante Laetitia L. , Smith Ellen , O'Shaughnessy Peter J. , Bellingham Michelle , Soffientini Ugo , Heidari Zeynab , Hamilton Graham , Svingen Terje , Mitchell Rod T. , Fowler Paul A.

Hypospadias is among the most common congenital malformations with a mean prevalence of 19.9 per 10,000 live births in Europe. The cause of many cases of hypospadias remains unclear but likely results from a combination of genetic susceptibility and environmental factors. Although rodent studies have provided great insights into external genitalia morphogenesis, extrapolations to the human genitals is challenging given significant anatomic and morphogenetic differences. With t...