Endocrine Abstracts

Devices such as continuous glucose monitoring systems and insulin pumps are being increasingly used, improving quality of life and diabetic control for those with Type 1 diabetes mellitus. Skin reactions can occur at the local site which could be allergic, irritant or infective in nature. The history is key in differentiating between these. Typically infective or irritant dermatitis tend to cause intermittent problems and may start within days of a new device being applied to ...

Introduction: Mixed gonadal dysgenesis (MGD) is a rare form of difference in sex development (DSD) characterised by mosaic karyotype of 45,X/46,XY and dysgenetic gonads. Gender dysphoria can be associated, the frequency of which is unknown. We describe 2 cases of MGD with gender dysphoria and the conundrum around pubertal induction.Case 1: An 8-year-old, reared as a girl, presented with longstanding concerns about appear...

Background: Children with type 1 diabetes mellitus (T1DM) are at increased risk of other autoimmune conditions including thyroid, coeliac and Addison’s diseases. Hyperpigmentation is a recognized feature of Addison’s disease. We present a case with unusual diabetes-technology related hyperpigmentation.Case report: A 12-year-old male with known T1DM (glutamic acid decarboxylase antibody positive), coeliac diseas...