Endocrine Abstracts

Introduction: Hypoparathyroidism (Hypo) is associated with a higher risk of chronic kidney disease (CKD) and renal stones, although the time to onset of these complications in the disease’s natural history has never been explored. Calcium-Phosphate product (CaxP) has been shown to be a risk factor for moderate renal disease in Hypo in a limited number of cross-sectional or case-control studies.Objective: To determine the time of onset of incident se...

Objective: The aim of the current study is to examine the effects of gender affirming hormone therapy in transgender persons on calcium and phosphate concentrations and their regulatory hormones.Design: A prospective cohort studyMethods: This study investigated changes in calcium and phosphate concentrations and their regulatory hormones in trans women and trans men during the first year of hormone therapy. Trans women received est...

Purpose: In previous studies, magnesium (Mg) was found to be lower in cases with more severe primary hyperparathyroidism (PHPT) and higher calcium (Ca) levels. This study evaluated the relationship between serum Mg and serum Ca and phosphorus (P) levels in PHPT and their utility in discriminating osteoporosis and nephrolithiasis.Methods: Patients who were followed up with PHPT between March 2019 and March 2023 were analyzed retrospectively. Biochemical d...

Background: Hypercalciuria is a relevant complication in patients with treated hypoparathyroidism. Hypercalciuria is usually estimated by 24 h urinary calcium excretion (24 hUCa). In contrast, in pediatric endocrinology the calcium-creatinine-ratio (CaCrR) is more often used due to feasibility. This study aims to compare these two approaches in adult patients with hypoparathyroidism.Methods: In 181 systematically evaluated patients with primary hypoparat...

Objectives: Preoperative detection of parathyroid gland adenomas in patients diagnosed with primary hyperparathyroidism (pHPT) represents a diagnostic challenge. The aim of the study was to assess the utility of contrast-enhanced ultrasound (CEUS) as the diagnostic tool for preoperative localization of parathyroid gland adenomas in conjuction with a conventional ultrasonography.Methods: Between the years 2021 and 2022, 33 adult patients (30 women and 3 m...

Background: Osteoporotic fracture risk is doubled in patients with recent fracture; however, post-fracture treatment rates remain dismal. Fracture Liaison Services (FLS) aim to close the secondary prevention ‘gap’ and reduce fracture risk. This study evaluates the efficacy of a computer algorithm-supported, Nurse Practitioner-managed FLS developed in Wolfson Medical Center (WMC).Methods: A computerized decision-making algorithm was developed us...