Incidence of maternal and fetal complications in diabetic pregnancies

Syrine Trabelsi; Olfa Lajili; Yesmine Jallouli; Sana Khamassi; Yosra Htira; Hedfi Imene; Chaima Jemai; Ali Zohra Hadj; Mami Feika Ben

doi:10.1530/endoabs.99.EP1060

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Endocrine Abstracts (2024) 99 EP1060 | DOI: 10.1530/endoabs.99.EP1060

ECE2024 Eposter Presentations Diabetes, Obesity, Metabolism and Nutrition (383 abstracts)

Incidence of maternal and fetal complications in diabetic pregnancies

Syrine Trabelsi , Olfa Lajili , Yesmine Jallouli , Sana Khamassi , Yosra Htira , Hedfi Imene , Chaima Jemai , Zohra Hadj Ali & Feika Ben Mami

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National Institute of Nutrition and Food Technology, C, Tunis

Introduction: Pre-existing diabetes during pregnancy can negatively affect the health of women and their babies. The aim of our study was to describe the incidence of maternal and fetal complications in women with diabetic pregnancies.

Methods: This was a retrospective descriptive study, including 30 patients followed at the 17SPO2 "Diabetes and Pregnancy" research unit in ward "C" over a 6-month period (January-June 2023).

Results: Mean age was 34.8±5.7 years with 66.7% T1DM and 33.3% T2DM. Mean HbA1c and fasting plasma glucose were 7.8±1.3% and 8.2 ±3.1 mmol/l. The mean weight gain at the end of pregnancy was 8.3 ±3.2 kg. More than half of patients (58.6%) were not educated about pregnancy planning. However, 86.2% of patients had regular medical follow-up during pregnancy. The main maternal complications associated with diabetes were lower urinary tract infections (44.8%) and gestational hypertension/pre-eclampsia (24.1%). Fetal complications were dominated by hypoglycemia, macrosomia, hydramnios and threatened preterm delivery in 48.8%, 48.3%, 31% and 24.1% of patients respectively, followed by neonatal jaundice (17.2%), spontaneous miscarriage/late-term abortion (6.8%) and fetal death in utero (6.9%). In addition, 20 patients delivered full-term by Caesarean section.

Conclusion: Our study showed that the main maternal-fetal complications observed during diabetic pregnancies were lower urinary tract infections, gravid hypertension and macrosomia. Education about pregnancy planning and close monitoring of these patients could improve the maternal and fetal prognosis of these high-risk pregnancies.