A case of ectopic adrenal tissue in the fallopian tube

Bruna Pimentel; Margarida Oliveira; Catarina Gama; Paula Sprovera; Antunes Carolina Monteiro; Guia Lopes Maria Leonor; Clara Cunha; Ana Brandao; Helena Oliveira; Sequeira Duarte Joao Manuel

doi:10.1530/endoabs.99.EP385

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Endocrine Abstracts (2024) 99 EP385 | DOI: 10.1530/endoabs.99.EP385

ECE2024 Eposter Presentations Adrenal and Cardiovascular Endocrinology (155 abstracts)

A case of ectopic adrenal tissue in the fallopian tube

Bruna Pimentel ¹ , Margarida Oliveira ¹ , Catarina Gama ¹ , Paula Sprovera ¹ , Carolina Monteiro Antunes ¹ , Maria Leonor Guia Lopes ¹ , Clara Cunha ¹ , Ana Brandão ² , Helena Oliveira ³ & João Manuel Sequeira Duarte ¹

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¹Egas Moniz Hospital, Endocrinology, Lisbon, Portugal; ²Hospital de Cascais, Gynecology and obstetrics, Lisbon, Portugal; ³Hospital de Cascais, Pathology, Lisbon, Portugal

Introduction: Ectopic adrenal tissue (EAT) occurs in less than 1% of adults, more commonly in males. It may be found anywhere along the path of embryogenic migration, usually in the kidney and retroperitoneal fat. We report a case of EAT in the fallopian tube, a particularly rare localization.

Case: We present a 57-year-old female with a known medical history of nephrolithiasis and previous ectopic pregnancies. The patient was submitted to a laparoscopic right adnexectomy due to a paratubal cyst. The histopathological evaluation of the surgical specimen showed a 7 cm fallopian tube partially adherent to the ovary, with a cystic structure in its distal half measuring 6.5 x 5 x 3.8 cm. A 3 mm nodule composed of clear cells was identified, immunoreactive to calretinin, inhibin, vimentin, ki67 1%, and negative for chromogranin, synaptophysin, S100, CD10, RCC and AE1/AE3 markers, suggesting an ectopic adrenal nodule. The patient had no symptoms of adrenal hyperfunction. On physical examination there was no evidence of hypertension or signs of Cushing’s syndrome.

Conclusion: EAT is usually clinically silent, found incidentally, and the diagnosis is made only by histopathological examination, like in our case. Very rarely, some ectopic EAT can become hormonally functional or undergo a malignant transformation. Hence, awareness is important and if detected resection is recommended.