Bacteriological and mycological profile of necrotizing otitis externa in diabetics

Malika El Omri; Jemli S; Bellakhdher Mouna; Meherzi Abir; Houas Jihene; Ghammem Monia; Ach Taieb; Kermani Wassim; Abdelkefi Mohamed

doi:10.1530/endoabs.99.EP781

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Endocrine Abstracts (2024) 99 EP781 | DOI: 10.1530/endoabs.99.EP781

ECE2024 Eposter Presentations Diabetes, Obesity, Metabolism and Nutrition (383 abstracts)

Bacteriological and mycological profile of necrotizing otitis externa in diabetics

El Omri Malika ¹ , Jemli S ¹ , Bellakhdher Mouna ¹ , Meherzi Abir ¹ , Houas Jihene ¹ , Ghammem Monia ¹ , Ach Taieb ² , Kermani Wassim ¹ & Abdelkefi Mohamed ¹

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¹ENT Department Farhat Hached Hospital, Sousse, Tunisia;
²Endocrinology Department Farhat Hached Hospital, Sousse, Tunisia

Introduction: Necrotizing otitis externa (NOE) is a rare but serious condition which is mainly seen in diabetics. This condition has a poor prognosis, due to the complexity of the terrain in which it occurs. The aim of our work is to study the clinical, paraclinical and therapeutic data of NOE.

Material and methods: This is a retrospective study covering 64 cases followed and treated in our ENT department over a period of 12 years between 2000 and 2022.

Results: Our serie includes 29 women and 33 men, with an average age of 67 years, 90% of our patients were diabetic. The bacteriological sample isolated Pseudomonas aeruginosa in 54% of cases. Culture was negative in 19 samples; among the latter, 10 cases had a mycotic origin. The temporal computed tomography scan performed for all patients was in favor of NOE in 22 cases and showed an extension of the infection in 29 cases. Fluoroquinolone was prescribed in all cases associated with a Cephalosporine 3rd generation (C3G) in 58 cases, and a C3G with Metronidazole in 6 cases. The treatment was revised in 15 patients, 9 patients had fungal involvement, 4 patients developed resistance to Ceftazidine and 2 cases were allergic to Ceftazidine. The total duration of antibiotic treatment was on average 54.43 days. Healing was achieved in 98.4%.

Conclusion: The bacteriological profile of NOE in diabetic patients a is predominated by the presence of Pseudomonas aeruginosa and characterized by the emergence of mycotic infections nowadays.