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Endocrine Abstracts (2025) 109 P111 | DOI: 10.1530/endoabs.109.P111

1Autonomous University of Bucaramanga, Bucaramanga, Colombia; 2University of Andes, Mérida, Venezuela; 3University of Santander, Bucaramanga, Colombia


Introduction: Bariatric surgery has been associated with improvements in obesity-related conditions, including obstructive sleep apnea syndrome (OSAS). This study aimed to explore the relationship between OSAS severity and body mass index (BMI) reduction in obese patients undergoing bariatric surgery.

Objective: To evaluate the impact of bariatric surgery on OSAS severity by assessing changes in the apnea-hypopnea index (AHI) and BMI over a two-year follow-up.

Materials and Methods: A total of 100 obese patients (59 men and 41 women) with a BMI ≥35 kg/m² and a mean age of 64 ± 3 years were included. Patients underwent either sleeve gastrectomy (SG) or gastric bypass (GB). Anthropometric data (BMI and weight changes) were collected preoperatively and during follow-up (at least two years). Statistical analysis was performed using non-parametric methods.

Results: Polysomnographic or cardiorespiratory studies revealed a significant reduction in OSAS severity post-surgery. The average AHI decreased from 19.3 ± 7.5 to 9.6 ± 4.8 (P < 0.001). Additionally, metabolic parameters improved following surgery.

Discussion: Bariatric surgery resulted in a marked improvement in OSAS severity across all patients, with some experiencing complete normalization of the AHI. This reduction in OSAS was closely associated with a decrease in BMI, supporting the effectiveness of weight loss interventions in managing sleep-disordered breathing.

Conclusion: Bariatric surgery significantly reduces OSAS severity, with some patients achieving full normalization of the AHI. These findings emphasize the importance of bariatric surgery as a therapeutic option for obese patients with OSAS.

Keywords: bariatric surgery, obstructive sleep apnea, apnea-hypopnea index, obesity, body mass index.

Volume 109

Society for Endocrinology BES 2025

Harrogate, UK
10 Mar 2025 - 12 Mar 2025

Society for Endocrinology 

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