Endocrine Abstracts

Introduction: East Sussex Healthcare NHS Trust started radioactive iodine treatment for benign thyroid disease following national training programme. QIP is to review the outcomes after RAI treatment and potential issues.

Data: 128 patient’s outcomes, at least completed six months following RAI treatment, were collected. 97 patients completed one year and 45 patients completed two years. Four patients’ data are not available, one moved out of area, one was discharged early. 74.2% female, 25.7% were male. 57.8 % had autoimmune thyrotoxicosis, 33.6% of patient had toxic multinodular goitre and 8.6% had toxic adenoma.

Results: One patient became pregnant within four weeks of treatment, despite having discussion avoiding pregnancy and had negative pregnancy test on the day of RAI treatment. However, she decided to have termination of pregnancy on her own. Five patients needed steroid treatment; three patients had pre-planned steroid cover to reduce the risk of flare up of non-active thyroid eye disease. 2 patients needed steroid cover after developing new thyroid eye disease. However, all 5 patients did not have any further problem. One patient had second dose of RAI in ESHT RAI service.

Conclusion: After 2 years of follow up all patients were treated, hence not to consider repeat second dose of RAI at least for 2years. However, more patients’ data would help to conclude that. Most of the patients with AIT would become hypothyroid and only 50-55% of Toxic adenoma/MNG patients became hypothyroid by 2yrs.