Risk factors for impaired glucose tolerance: a cross-sectional study

Zirong Li; Yu Xie; Yue Fan; Lu Jing; Shangjian Liu

doi:10.1530/endoabs.109.EP13

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Endocrine Abstracts (2025) 109 EP13 | DOI: 10.1530/endoabs.109.EP13

SFEBES2025 ePoster Presentations Metabolism, Obesity and Diabetes (14 abstracts)

Risk factors for impaired glucose tolerance: a cross-sectional study

Zirong Li ¹ , Yu Xie ² , Yue Fan ² , Lu Jing ³ & Shangjian Liu ³

Author affiliations

¹Graduate School of Beijing University of Chinese Medicine, Beijing, China; ²Department of Endocrinology, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China; ³Department of Cardiovascular Medicine, Eye Hospital China Academy of Chinese Medicine Sciences, Beijing, China

Background: This study aims to analyze the risk factors for elevated fasting plasma glucose (FPG) and 2-hour post-load plasma glucose (2hPG) in IGT patients respectively.

Methods: A cross-sectional study was conducted with 463 IGT patients in China between January 2021 and August 2021. Data collected included demographics and medical history, blood glucose, glycated hemoglobin, liver function, renal function, and blood lipids. Univariate and multivariate regression analyses were used to evaluate the associated risk factors for FPG and 2hPG. Finally, the patient’s information was entered into an EXCEL table, and the data were analyzed using SPSS 26.0 statistical software.

Results: Male gender, older age, and higher 2hPG were independent risk factors for elevated FPG levels. Higher FPG, higher LDL-C, and a history of hypertension were independent risk factors for elevated 2hPG levels.

Conclusions: Male gender, older age, higher FPG, higher 2hPG, higher LDL-C, and history of hypertension were independent risk factors for IGT patients. We need to pay attention to 2hPG and recommend OGTT as an early screening tool to identify high-risk individuals.