Endocrine Abstracts

Glucocorticoids are widely prescribed as anti-inflammatory and immunosuppressive agents. This results in at least 1% of the population using chronic glucocorticoid therapy being at risk for glucocorticoid-induced adrenal insufficiency, a condition associated with considerable morbidity and mortality if not promptly recognised and managed. In cases where glucocorticoid-induced adrenal insufficiency develops or is suspected, a thorough clinical evaluation is essential, encompassing detailed history-taking, physical examination, and, where appropriate, biochemical testing. For patients discontinuing glucocorticoid therapy, individualised tapering protocols are crucial to minimise withdrawal symptoms and support adrenal function recovery. Patient education is a cornerstone of care, addressing key topics such as iatrogenic Cushing’s syndrome, adrenal crisis prevention, and glucocorticoid withdrawal syndrome. This talk will focus on glucocorticoid-induced adrenal insufficiency management, with emphasis on national and international clinical guidelines.