Endocrine Abstracts

Turner Syndrome (TS) is characterized by a karyotype containing one X chromosome and complete or partial absence of the second sex chromosome, associated with one or more typical clinical manifestations of TS in a phenotypic girl/woman. It is common, affecting 50/100 000 females and unlike many conditions managed by endocrinologists it requires life-long care, can affect many different organs, with different conditions arising at different stages of life and often requiring multidisciplinary input. The recent 2024 International Guidelines for Management of Turner Syndrome provide a useful resource to help inform best practice, and covers the areas of (1) diagnosis and genetics, (2) growth, (3) puberty and estrogen treatment, (4) cardiovascular health, (5) transition, (6) fertility assessment, monitoring, and counselling, (7) health surveillance for comorbidities throughout the lifespan, and (8) neurocognition and its implications for mental health and well-being. The session will enable discussion of the updated guidelines including a selection of key issues/updates as well as ongoing questions to enable optimisation of care for all girls and women with TS.